[article]
| Titre : |
Can inorganic powders provide any biological benefit in stratum corneum, while residing on skin surface ? |
| Type de document : |
texte imprimé |
| Auteurs : |
Eriko Kawai, Auteur ; Yoshiyuki Kohno, Auteur ; Katsuki Ogawa, Auteur ; Kenichi Sakuma, Auteur ; Norinobu Yoshikawa, Auteur ; Daisuke Aso, Auteur |
| Année de publication : |
2002 |
| Article en page(s) : |
p. 269-275 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Activateur de plasminogène
Peau -- Soins et hygiène
Poudres -- Emploi en cosmétologie
Sécheresse cutanéeUne xérose est un dessèchement de la peau.
Elle peut avoir différentes causes, comme certaines pathologies (dermatite atopique aussi appelé eczéma atopique), des carences, notamment en Vitamine A, ou des facteurs externes, comme les contacts avec des substances irritantes ou le traitement par certains médicaments.
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The plasminogen (Plg) activation system plays a role in the process leading to dry skin with impaired barrier function, and serine protease inhibitors are known to improve dry skin. In this study, we have discovered that a urokinase-type Plg activator (UK), a trigger of the Plg activation system, which was previously believed to work within the epidermis, also exists in stratum corneum (SC). Focusing on the UK reaction in SC, we sought to develop a method of dry skin prevention. First, the removal of UK by adsorption with inorganic powders was investigated. Screening of powders, revealed that silicia and talc afforded superior UK adsorption. Futhermore, zinc oxide showed superior UK inhibition. The combination of these two different powders enabled us to develop the composite powder, "Skin Care Powder" (SCP), which has an excellent performance in both UK adsorption and UK inhibition. The daily application of a powdery foundation containing SCP for 2 months resulted in a significant suppression of increased transepidermal water loss and a better texture compared to the control. Our results demonstrated that certain inorganic powders can bring significant biological benefit to the skin, whilst remaining on the skin surface. |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10621 |
in IFSCC MAGAZINE > Vol. 5, N° 4 (10-11-12/2002) . - p. 269-275
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