[article]
| Titre : |
Synthesis of 3-aminopropyl-menthyl-phosphate and its irritation-reducing activities |
| Type de document : |
texte imprimé |
| Auteurs : |
Jae Won You, Auteur ; Duck Hee Kim, Auteur ; Su Sun An, Auteur ; Ih Seop Chang, Auteur ; Hak-Hee kang, Auteur ; Ok Sub Lee, Auteur |
| Année de publication : |
2003 |
| Article en page(s) : |
p. 15-18 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Aminoalkyle-menthyl-phosphate
Anti-inflammatoires
Peau -- Inflammation
Visage -- Soins et hygiène
Vitamine A
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
A cosmetic raw material, aminoalkyl-menthyl-phosphate was synthesized and its irritation-reducing property was investigated. Aminoalkyl-menthyl-phosphate was prepared by the reaction of menthyl phosphorodichloride and aminoalcohol, followed by hydrolysis. Among them, 3-aminopropyl-menthyl-phosphate showed a significant effect to reduce the irritation caused by retinol and AHA, which is comparable to that of hydrocortisone, a steroidal anti-inflammatory drug. In addition, its synthetic scheme was very simple and economic and we could prepare 3-aminopropyl-menthyl-phosphate with high purity and good yield. Inclusion of such an ingredient in cosmetics that contain biologically active compounds such as retinol and AHA may result in preparations with a lower irritation potential. |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10611 |
in IFSCC MAGAZINE > Vol. 6, N° 1 (01-02-03/2003) . - p. 15-18
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