Long-term retinol decomposition profile and emulsion chassis & package impact to destabilization / Hoyun Kim in SOFW JOURNAL, Vol. 143, N° 11 (11/2017)  

[article]  inSOFW JOURNAL > Vol. 143, N° 11 (11/2017) . - p. 18-25 Titre : Long-term retinol decomposition profile and emulsion chassis & package impact to destabilization Type de document : texte imprimé Auteurs : Hoyun Kim, Auteur ; Shinyoung Park, Auteur ; Taeseok Kim, Auteur ; Hyungju Ahn, Auteur Année de publication : 2017 Article en page(s) : p. 18-25 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Chimie analytique Emulsions -- Emploi en cosmétologie Encapsulation Formulation (Génie chimique) Statistique Vitamine A Vitamine A -- Stabilité Index. décimale : 668.5 Parfums et cosmétiques Résumé : Objective : Retinol (vitamin A) is known as safe and best anti-aging functional ingredient for cosmetic application. However retinol is unstable under environmental condition - temperature, light, components and aged time ect. Therefore, there have been many efforts to stabilize retinol against oxidation by applying the liposomes utilizing many kinds of applicable ingredients. However, most of the studies were limited to a period within 1-3 months with some typical anto-oxidants and there was rarely a study conducted over 12 months, although cosmetics were often used much longer. In this study we chose triply encapsulated retinol with polycaprolactone, lecithin and silica, and applied to 5 bio-mimetic cosmetic oil-in-water emulsions to find solutions against the decomposition of retinol. Note de contenu : - MATERIALS AND METHODS - METHODS : Preparation of cosmetic emulsion - Package component impact to retinol stability - Analysis by polar microscopic view - Analysis by SAXS and WAXS - Retinol concentration assay - HPLC method analysis - Measures by UV vis absorption spectrophotometer - Statistical analysis - RESULTS AND DISCUSSION : Microscopic view analysis - SAXS & WAXS analysis - Decomposition profile of encapsulated retinol under different temperatures - Retinol stability profile under UV-visible spectrophotometer - Comparison of retinol stability plot between LC and UV-visible spectrophotometer - Decomposition profile of encapsulated retinol per package component - Table : Formulation on cosmetic chassis En ligne : https://drive.google.com/file/d/137S6NtxKYnOie89ZHkOTB2Y_y8QUBlHe/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=29388 [article]

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Maximum stability, bioavailability and lower irritation from retinol / Michael Sacher in SOFW JOURNAL, Vol. 143, N° 3 (03/2017)  

[article]  inSOFW JOURNAL > Vol. 143, N° 3 (03/2017) . - p. 22-28 Titre : Maximum stability, bioavailability and lower irritation from retinol Type de document : texte imprimé Auteurs : Michael Sacher, Auteur ; Joaquin Pérez Sanchez, Auteur ; Arnoldo Fonseca, Auteur Année de publication : 2017 Article en page(s) : p. 22-28 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Biodisponibilité Peau -- Inflammation Peau -- Soins et hygiène Vitamine A Vitamine A -- Stabilité Index. décimale : 668.5 Parfums et cosmétiques Résumé : Retinol is among the most well-known and studied cosmetic ingredients available to formulators, and consumers have come to trust retinol as a powerful solution to improve the appearance of their skin. Achieving these benefits, nonetheless, requires formulators to maximize the stability and bioavailability of retinol, while at the same time taking care to avoid possible irritation-related concerns. This is particularly true for formulations, which utilize a high-load of retinol. This study reviews the performance of a recently launched offering, InuMax Advanced Retinol Cosmetic Active, in addressing these requirements. Standard methods for stability are used alongside more novel visualization techniques, enabling in vivo investigation of bioavailability and irritation. These tests demonstrate that the new product enables effective performance in retinol stability, retinol bioavailability, and reduction of adverse irritation, providing formulators with a new, powerful option for their retinol-containing formulations. Note de contenu : - MATERIALS AND EXPERIMENTAL METHODS : Stability test - Bioavailability test - Reduction of irritation potential - RESULTS AND DISCUSSION : Stability test - Bioavailability test - Reduction of irritation potential En ligne : https://drive.google.com/file/d/1unTKnOUQNraeoYe-wDvhXGQG8mfb4bo_/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28198 [article]

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