| Titre : |
Melanosome transportation control via innovative active |
| Type de document : |
texte imprimé |
| Auteurs : |
Kiyotaka Tanaka, Auteur ; Arunasiri Iddamalgoda, Auteur |
| Année de publication : |
2015 |
| Article en page(s) : |
p. 41-44 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Agents de blanchiment
Biomolécules actives
Kinésine
Mélanosome
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Various biological parts and structures are formed within cells and transported to parts of the body by driving proteins called motor proteins. For example, melanin pigment that influences skin tone is produced in melanocytes and passed to keratinocytes through dendrites. Keratinocytes absorb melanin from surrrounding areas (or tips of dendrites including melanin) and darken.
Usually, melanin generated in melanocytes is transported to the end of dendrites. In this process, melanosomes are transported by kinesin, a type of motor protein.
Melanin is transported along dendrites while it is synthesised in sacks called melanosomes. Kinesin is involved in the transport of melanosomes to the end of dendrites (Fig. 1). Kinesin is a protein with limb-like strutures. Kinesin holds up melanosome using hand-like strutures (light chains) and walks on microtubules using leg-like structures (heavy chains).
Kinesins travel in a specific direction, always toward the end of dendrites, namely keratinocytes. They move leg-like structures alternately as though they are walking; Since they look like micro robots, they are also know as 'biological nanomachines'. |
| Note de contenu : |
- Kinesin as a new target of skin lightening
- Development of a plant based kinesin inhibitor
- Inhibition of melanin transportation
- Skin lightening effect on 3D skin model
- Clinical study on human skin
- Identifying active molecule
- Relationship between skin lightening and 'Cinderella time'
- New skin lightening theory |
| En ligne : |
https://drive.google.com/file/d/1PfSLWr4J3wXvuzO_h1qWuqxOgrx7Ohl4/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=24936 |
in PERSONAL CARE EUROPE > Vol. 8, N° 6 (11/2015) . - p. 41-44
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