Dyes, flies, and sunny skies : photodynamic therapy and neglected tropical diseases / Mark Wainwright in COLORATION TECHNOLOGY, Vol. 133, N° 1 (02/2017)  

[article]  inCOLORATION TECHNOLOGY > Vol. 133, N° 1 (02/2017) . - p. 3–14 Titre : Dyes, flies, and sunny skies : photodynamic therapy and neglected tropical diseases Type de document : texte imprimé Auteurs : Mark Wainwright, Auteur Année de publication : 2017 Article en page(s) : p. 3–14 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Maladies tropicales Photochimiothérapie Index. décimale : 615.5 Thérapeutique : classer à 616.618 les thérapies des diverses maladies Résumé : Photodynamic therapy, in its various applications, represents the focused combination of electromagnetic radiation, a chemical (usually a dye) capable of its absorption and conversion, and oxygen to provide cytotoxicity (cell killing). The effect has been known for over a century, and there is considerable clinical use in terms of its application to various cancers. However, the antimicrobial properties of the technology, which are considerable, have received only a lukewarm reception by healthcare providers, and the possibilities for tropical disease therapy are mainly unexplored. This is particularly vexatious given both the inexpensive nature of the photosensitisers and light sources available and the lack of conventional forward progress in widespread diseases such as leishmaniasis, trypanosomiasis, and tuberculosis in the Developing World. The following review therefore covers the use, or potential use, of the photodynamic approach in this area, mainly with reference to tropical diseases having current ‘neglected’ status according to the World Health Organisation. Note de contenu : - PHOTOSENSITISERS AND THE PHOTODYNAMIC EFFECT - TROPICAL DISEASE AND NEGLECTED STATUS - INFECTION AND TRANSMISSION - IDENTIFYING POTENTIAL APPROACHES - TOPICAL/LOCAL THERAPY : Acceptable photosensitisers - Approaches - Bacterial infection - Protozoal infection - Worm infection - Blood product decontamination - Water purification - Do it yourself DOI : 10.1111/cote.12259 En ligne : https://drive.google.com/file/d/1zqCvWMa9G6O7jE9H2qVu1ok11u3djnk6/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=27875 [article]

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Synthesis and photophysical properties of meso-aminophenyl-substituted heptamethine dyes as potential leads to new contrast agents / Okoh Okoh Adeyi in COLORATION TECHNOLOGY, Vol. 135, N° 4 (08/2019)  

[article]  inCOLORATION TECHNOLOGY > Vol. 135, N° 4 (08/2019) . - p. 305-311 Titre : Synthesis and photophysical properties of meso-aminophenyl-substituted heptamethine dyes as potential leads to new contrast agents Type de document : texte imprimé Auteurs : Okoh Okoh Adeyi, Auteur ; Megan E. Critchley, Auteur ; Roger H. Bisby, Auteur ; Clare L. Lawrence, Auteur ; Mark Wainwright, Auteur ; Robert B. Smith, Auteur Année de publication : 2019 Article en page(s) : p. 305-311 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Colorants -- Synthèse Fluorescence Heptaméthine Index. décimale : 667.2 Colorants et pigments Résumé : The series of rigid meso‐aminophenyl‐substituted heptamethine dyes presented herein exhibit surprising fluorescence properties, demonstrating larger Stokes shifts when compared with both structurally similar rigid meso‐chlorophenyl and linear heptamethine dyes. Based on their photophysical properties, these are of considerable importance to the development of contrast agents, within biology and medicine. DOI : 10.1111/cote.12403 En ligne : https://onlinelibrary.wiley.com/doi/epdf/10.1111/cote.12403 Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=32833 [article]

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Therapeutic applications of near-infrared dyes / Mark Wainwright in COLORATION TECHNOLOGY, Vol. 126, N° 3 (2010)  

[article]  inCOLORATION TECHNOLOGY > Vol. 126, N° 3 (2010) . - p.115-125 Titre : Therapeutic applications of near-infrared dyes Type de document : texte imprimé Auteurs : Mark Wainwright, Auteur Année de publication : 2010 Article en page(s) : p.115-125 Note générale : Bibliogr. Langues : Anglais (eng) Index. décimale : 667.3 Teinture et impression des tissus Résumé : The interaction of dyes with cells and tissue is well understood, and the use of light-activated compounds in therapy is becoming more established. However, the application of near-infrared light in these areas, particularly from a therapeutic angle, has received little attention. With greatly improved access to near-infrared light sources, there is considerable potential for therapeutic advances due to the increased tissue penetration offered by wavelengths in the 700–1000 nm region, particularly regarding blood vessel disorders and larger or deeper-seated tumours. The design and development of suitably absorbing dyes to take advantage of near-infraread illumination is discussed for the major structural types. DOI : 10.1111/j.1478-4408.2010.00244.x En ligne : http://onlinelibrary.wiley.com/doi/10.1111/j.1478-4408.2010.00244.x/pdf Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=9456 [article]

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