3 résultat(s) recherche sur le tag ''Physiologie'

Relationship between clinical features of facial dry skin and biophysical parameters in Asians / J. H. Baek in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 33, N° 3 (06/2011)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 33, N° 3 (06/2011) . - p. 222-227 Titre : Relationship between clinical features of facial dry skin and biophysical parameters in Asians Type de document : texte imprimé Auteurs : J. H. Baek, Auteur ; M. Y. Lee, Auteur ; J. S. Koh, Auteur Année de publication : 2011 Article en page(s) : p. 222-227 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Biotechnologie Peau -- Physiologie Sécheresse cutanée Une xérose est un dessèchement de la peau. Elle peut avoir différentes causes, comme certaines pathologies (dermatite atopique aussi appelé eczéma atopique), des carences, notamment en Vitamine A, ou des facteurs externes, comme les contacts avec des substances irritantes ou le traitement par certains médicaments. Tags : 'Peau  asiatique'  'Femme  coréenne'  sèche'  'Physiologie  peau'  'Bioingénierie'  Balance  'Etude  clinique' Index. décimale : 668.5 Parfums et cosmétiques Résumé : Il y a eu peu de données permettant de classer les caractéristiques biophysiques de la peau saine des femmes coréennes. Par conséquent, le but de cette étude était de trouver les paramètres les plus utiles basés sur une évaluation clinique pour organiser les types de peau. Cent trois femmes volontaires âgées de 20 à 59 ans ont participéà cette étude. Nous avons conduit un questionnaire d’auto-évaluation, une évaluation clinique de la peau du visage et des mesures non-invasives sur la joue dans des conditions contrôlées. L’analyse globale du questionnaire a indiqué que 72% des personnes interrogées avaient la peau sèche. Cependant, les résultats de l’évaluation clinique ciblée sur la rugosité et l’évaluation de la joue ont montré que 6 sujets avaient la peau très sèche (6%), 29,la peau sèche (28%) et 68 la peau normale pour une humidité suffisante (66%). En analysant la corrélation entre l’évaluation clinique et les paramètres biophysiques, nous avons obtenu six paramètres biophysiques avec des corrélations relativement plus hautes que les autres. Notre étude a ainsi fourni des informations générales sur les caractéristiques physiologiques de peau normale des femmes coréennes et a suggéré des paramètres utiles pour caractériser leur peau sèche. Note de contenu : - MATERIALS AND METHODS : self-evaluation - Clinical assessment - Non-invasive measurements - Statistical analysis. - RESULTS : Clinical assessment of facial skin - Non-invasive measurements. DOI : 10.1111/j.1468-2494.2010.00608.x En ligne : http://onlinelibrary.wiley.com/doi/10.1111/j.1468-2494.2010.00608.x/pdf Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=11685 [article]

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012966	-	Périodique	Bibliothèque principale	Documentaires	Disponible

2,5-diketopiperazines mitigate the amount of advanced glycation end products accumulated with age in human dermal fibroblasts / A. André in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 42, N° 6 (12/2020)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 42, N° 6 (12/2020) . - p. 596-604 Titre : 2,5-diketopiperazines mitigate the amount of advanced glycation end products accumulated with age in human dermal fibroblasts Type de document : texte imprimé Auteurs : A. André, Auteur ; A. K. Touré, Auteur ; D. Stien, Auteur ; V. Eparvier, Auteur Année de publication : 2020 Article en page(s) : p. 596-604 Note générale : Bibliogr. Langues : Anglais (eng) Tags : '2,5-dicétopipérazines'  AGE  'Culture  cellulaire'  'Analyse  chimique'  'Clairance  de  la  LMC'  'Réseaux  moléculaires'  'Physiologie  cutanée' Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : Glycation is a common non-enzymatic reaction between proteins and sugars, resulting in the formation of advanced glycation end products (AGEs) in the human body. As can be seen in diabetic patients, the accumulation of AGEs in the skin has aesthetic consequences (wrinkles, brown spots and yellowish complexion). Therefore, the objective of this work was to find compounds isolated from natural sources that could eliminate the final AGEs accumulated in the skin with ageing. - Methods and results : A preliminary screening performed on a bank of microbial extracts and pure compounds showed that 2,5-Diketopiperazines (DKPs), as well as the extract of Sphingobacterium sp (SNB-CN13), reduced the presence of AGEs in fibroblasts by −28% and −23%, respectively. In this article, we present the dereplication approach used to reveal the presence of 26 different DKPs in the crude extract of Sphingobacterium sp. Bioguided fractionation has led to the isolation of 12 of them, whose identity has been confirmed by HRMS and NMR. A green synthesis approach has been developed to synthesize 3 symmetrical DKPs. The biological activity of all DKPs was evaluated by the development of an in vitro test using immunocytochemistry to reveal the presence of AGE carboxymethyl-lysine in human dermal fibroblasts. - Conclusion : Our work shows for the first time that DKPs decrease the amount of carboxymethyl-lysine AGE in elderly human dermal fibroblasts grown in vitro. Therefore, diketopiperazines can be considered as compounds of interest for dermatological and cosmetic applications with an anti-ageing aim. Note de contenu : - General experimental procedures - Isolation and identification of Sphingobacterium spp. SNB-CN13 - Culture of bacterium, extraction and isolation of compounds - Cell preparation method - Biological activity – Immunofluorescence of CML - UPLC-MS/MS analysis of SNB-CN13 extract - MZmine 2 Data preprocessing Parameters - Molecular Network analysis - Table 1 : Percentage of decrease in CML in fibroblasts treated with molecules 1-21 DOI : https://doi.org/10.1111/ics.12655 En ligne : https://drive.google.com/file/d/1KRaXAe5gJYR7kxdb7S1cKkwbRtkBQsFX/view?usp=shari [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35426 [article]

Advances in dry skin technology extend beyond the category of cosmetic products / Kenji Kitamura in IFSCC MAGAZINE, Vol. 5, N° 3 (07-08-09/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 3 (07-08-09/2002) . - p. 177-187 Titre : Advances in dry skin technology extend beyond the category of cosmetic products Type de document : texte imprimé Auteurs : Kenji Kitamura, Auteur Année de publication : 2002 Article en page(s) : p. 177-187 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Acné L'acné (nom féminin) est une dermatose (maladie de la peau) inflammatoire des follicules pilosébacés (glandes sécrétant le sébum, à la racine des poils) avec formation de comédons. Cette maladie de la peau est représentée dans sa forme la plus fréquente par l'acné polymorphe juvénile qui touche les adolescents, mais qui ne résume pas toutes les acnés. Il existe aussi des acnés exogènes d'origine professionnelle, médicamenteuse, cosmétique... Activateur de plasminogène Biomolécules actives Peau -- Histopathologie Peau -- Maladies Peau -- Soins et hygiène Sécheresse cutanée Une xérose est un dessèchement de la peau. Elle peut avoir différentes causes, comme certaines pathologies (dermatite atopique aussi appelé eczéma atopique), des carences, notamment en Vitamine A, ou des facteurs externes, comme les contacts avec des substances irritantes ou le traitement par certains médicaments. Tags : 'Peau  sèche  et  rugueuse'  'Activateur  de  plasminogène'  't-AMCHA'  'Fonction  barrière'  'Physiologie  la  peau  acné/boutons' Index. décimale : 668.5 Parfums et cosmétiques Résumé : The prevention and improvement of « rough and dry skin » occupies a key position in the basic function of skin care cosmetics. Therefore, research on skin physiology and the development of active ingredients for products for the treatment of rough and dry skin conditions are important and universal topics. With the purpose of clarifying the role of internal factors in the process of dry skin occurs, we investigated from a pharmacological perspective as a new experimental strategy. Through this research, we have conceived a new theory explaining how dry skin occurs. Furthermore, on the basis of this theory, we have developed a new effective compound for its treatment. In order to study on the mechanism by which dry skin occurs, we used anti-inflammatory agents and inhibitors against histological impairment mediators, as well as various substances that were considered to regulate the function of epidermal cells. The results showed that protease inhibitors, especially the plasminogen (PLG) activation system-specific inhibitors, were effective against dry skin caused by extrinsic factor. Furthermore, its effects closely correlated with the inhibition activity against the PLG activation system. In addition, we demonstrated immunohistologically that the PLG activation system, which was only located along the epidermal basal layer of normal skin, was widely distributed throughout all layers of epidermis while dry skin induction. These results strongly suggested that the occurrence of dry skin involves a cause bringing about the over-manifestation of the epidermal PLG activation system, which in turn causes abnormalities in the regulating mechanisms for the proliferation and differentiation of epidermal cells, and these result in dry skin. We discovered trans-4-aminomethylcyclohexanecarboxylic acid (t-AMCHA), which was the most effective substance in view of the theory on the occurrence of dry skin. Then we investigated in detail the efficacy of t-AMCHA. The results of our studies confirmed that t-AMCHA strongly suppresses the over-manifestation of the PLG activation system in the epidermis when dry skin was occurring. In addition, t-AMCHA demonstrated superb effectiveness against phenomena caused by dry skin, including the loss of moisture from the horny layer, the increase in transepidermal water loss (TEWL), accelerated turnover in the horny layer, and the changes in various other indicators such as epidermal hypertrophy. These results strongly supported the effectiveness of t-AMCHA on dry skin. Based on these research findings, we have further developed a novel active ingredient, t-AMCHA, which is being widely applied to skin care products. Furthermore, subsequent research on the efficacy of t-AMCHA has confirmed this compound to be effective in promoting restoration and recovery of the barrier function of the stratum corneum, which is a key role of the horny layer. We have also conducted research on the skin physiology of acne and/or pimples of the pilosebaceus unit, which are the main skin problem for Japanese females in their 20s and 30s. Examination of the skin condition of females who are prone to develop these problems demonstrates a relative lowering of several physiological functions of the horny layer. These results indicate the necessity of incorporating new skin care technology designed to targets improvement on the horny layer function. With the background, we focused on the effectiveness of t-AMCHA in improving functions of the horny layer and developed new products by incorporating rough rough skin control technology into conventional and basic counter-acne techniques. In-use studies of these products showed favorable results. Through the application in anti-acne products, research and development of counter rough skin technology as a basic function of skin care products is being extend beyond the category of cosmetic products. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10641 [article]

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Code-barres	Cote	Support	Localisation	Section	Disponibilité
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