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Partager le résultat de cette rechercheL'énergie photovotaïque : les responsabilités nouvelles de la chimie ! / Daniel Lincot in L'ACTUALITE CHIMIQUE, N° 353-354 (06-07-08/2011)
Titre : L'énergie photovotaïque : les responsabilités nouvelles de la chimie ! Type de document : texte imprimé Auteurs : Daniel Lincot, Auteur Année de publication : 2011 Article en page(s) : p. 52-60 Note générale : Bibliogr. Langues : Français (fre) Catégories : Conversion photovoltaïque
Couches minces
Energie solaire
PhotopilesTags : 'Énergie solaire photovoltaïque' 'Cellules solaires' 'Couches minces' 'Procédés chimiques' CIGS 'Photovoltaïque organique' colorants' Index. décimale : 531.68 Transformation de l'énergie Résumé : La conversion photovoltaïque de l'énergie solaire connaît un développement industriel très rapide. La chimie y joue un rôle de plus en plus important, illustré par des exemples concrets issus des différentes filières actuelles (silicium cristallin ; couches minces basées sur le silicium amorphe, le diséléniure de cuivre, d'indium et de gallium Cu(In,Ga)Se2, et le tellurure de cadmium CdTe) et par son implication fondamentale dans le développement récent des filières organiques ou hybrides. À partir des questions allant de la purification des matériaux, des procédés de fabrication, des propriétés fondamentales des matériaux et des interfaces, jusqu'aux nouveaux concepts inspirés de la photosynthèse, quelques grandes lignes d'action à venir pour la chimie sont dessinées dans cet article. Note de contenu : - PANORAMA DES DIFFERENTES TECHNOLOGIES PHOTOVOLTAÏQUES
- LA FILLIERE SILICIUM : DE LA DISTILLATION A LA CHIMIE DES PLASMAS : Les procédés d'élaboration - Les couches minces
- LA FILIERE DES SEMI-CONDUCTEURS MULTINAIRES : A LA CONQUÊTE DU TABLEAU DE MENDELEÏEV ?
- LES FILIERES ORGANIQUES ET HYBRIDES : L'AVENEMENT DES "CELLULES DE CHIMISTES" : Les cellules à colorants - Les cellules solaires organiques
- LE DEVELOPPEMENT DES RECHERCHES SUR LA PRODUCTION DIRECTE DE CARBURANTS SOLAIRES
- LE GRAAL DES TRES HAUTS RENDEMENTS PHOTOVOLTAÏQUES : DE NOUVEAUX DEFIS POUR LES CHIMISTESEn ligne : https://new.societechimiquedefrance.fr/numero/lenergie-photovotaique-les-respons [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=11820
in L'ACTUALITE CHIMIQUE > N° 353-354 (06-07-08/2011) . - p. 52-60[article]Réservation
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Titre : 4-(1-phenylethyl)1,3-benzenediol : a new, highly efficient lightening agent Type de document : texte imprimé Auteurs : Gabriele Vielhaber, Auteur ; Gerhard Schmaus, Auteur ; karin jacobs, Auteur ; Helge Franke, Auteur ; Sabine Lange, Auteur ; Martina Herrmann, Auteur ; Holger Joppe, Auteur ; Oskar Koch, Auteur Année de publication : 2006 Article en page(s) : p. 227-234 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Allègement de peau' Tyrosinase 'Cellules mélanome B16' 'Modélisation d'épiderme en 3D' 'Etudes in vivo' Index. décimale : 668.5 Parfums et cosmétiques Résumé : There is an increasing world-wide demand for skin lightening active ingredients. Many common lightening ingredients on the market are either unsafe or ineffective at low concentrations. We therefore screened a series of hydroxy-stilbene derivatives for tyrosinase inhibitory activity. By chemical synthesis, the structures were optimized for efficacy and stability. The final candidate, 4-(1-phenylethyl)1,3-benzenediol, was found to be stable and to inhibit mushroom tyrosinase 22 times more effectively than kojic acid. In an assay with B16V melanoma cells, 4-(1-phenylethyl)1,3-benzenediol was the most potent inhibitor of melanin synthesis with an IC50 of 2 μM among the compounds investigated. The lightening effect of 4-(1-phenylethyl)1,3-benzenediol was not due to cytotoxicity as proved by an MTT assay on B16V cells. On pigmented 3D epidermis models, 0.1% of 4-(1-phenylethyl)1,3-benzenediol led to an almost complete suppression of melanin synthesis after 14 days of incubation. Finally, an in vivo test on Asian subjects proved that 4-(1-phenylethyl)1,3-benzenediol efficiently lightens human skin at 0.5% dosage. Optimal results are achieved when 4-(1-phenylethyl)1,3-benzenediol is applied in formulations with low oil content. In summary, we have demonstrated that 4-(1-phenylethyl)1,3-benzenediol is a potent, stable and safe skin lightener.
Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10448
in IFSCC MAGAZINE > Vol. 9, N° 3 (07-08-09/2006) . - p. 227-234[article]Réservation
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Titre : Differential toxicity on monocytes and monocyte-derived dendritic cells : a new tool to differentiate allergens from irritants ? Type de document : texte imprimé Auteurs : Laetitia Furio, Auteur ; J. Guesnet, Auteur ; Blandine Ducarre, Auteur ; A. Guezennec, Auteur ; Daniel Schmitt, Auteur ; josette Peguet-Navarro, Auteur Année de publication : 2007 Article en page(s) : p. 27-33 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Hypersensibilité cutanée' 'Méthode alternative in-vitro' 'Cellules dendritiques' Monocytes Apoptose Index. décimale : 668.5 Parfums et cosmétiques Résumé : Phenotypic activation of monocyte-derived dendritic cells has been proposed as an in vitro alternative assay to discriminate potential sensitizers from irritants, but the sensitivity of the assay remains controversial. In this study, we first determined the dynamic range of expression of activation/maturation markers on human monocyte-derived dendritic cells cultured in the presence or absence of transforming growth factor ß (TGFβ)? On day three of culture, most monocytes had already differentiated into dendritic cells that expressed low levels of costimulatory molecules especially in the presence TGFβ-treatment of 3-day-old TGFβ-treated monocyte-derived dendritic cells with several chemicals at sub-toxic concentrations induced significant phenotypic changes for all the strong and mild sensitizers tested, whereas the irritant sodium lauryl sulfate had no effect. However, a very large variability was observed among the experiments. Most interestingly, we could show here for the first time that at concentrations sub-toxic for monocyte-derived dendritic cells all the allergens tested induced monocyte apoptosis within 2 days of culture. In contrast, sodium lauryl sulfate displayed similar toxicity on monocytes and monocyte-derived dendritic cells and these results were confirmed with other irritants such as benzoic acid or methylsalicylate. Although testing of far more chemicals is required, these results indicate that differential toxicity of chemicals to monocytes and monocyte-derived dendritic cells could be a rapid, simple and valuable tool to differentiate sensitizers from irritants. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10425
in IFSCC MAGAZINE > Vol. 10, N° 1 (01-02/2007) . - p. 27-33[article]Réservation
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Titre : Down regulation of nuclear factor-kappaB activation in human keratinocytes by melanogenesis inhibitors Type de document : texte imprimé Auteurs : Kwang Seok Ahn, Auteur ; Jinseon Lee, Auteur ; Yeong Shik Kim, Auteur Année de publication : 2004 Article en page(s) : p. 39-45 Note générale : Bibliogr. Langues : Anglais (eng) Tags : Kératinocyte 'Inhibiteurs de la mélanogenèse' 'Activité NK-?B' 'Cellules transfectantes' 'Lumière ultraviolette B' Index. décimale : 668.5 Parfums et cosmétiques Résumé : Liberated nuclear factor-kappaB (NF-κB) is translocated into the nucleus where it can change or alter the expression of target genes, resulting in the secretion of extracellular signaling molecules including melanotrophic factors affecting the melanocyte. In order to demonstrate the possible role of NF-κB activation on the synthesis of melanotrophic factors from the keratinocytes, the activities of NF-κB induced by melanogenesis inhibitors were determined in human HaCaT keratinocytes transfected with pNF-κB-SEAP-NPT plasmid. Transfectant cells released the secretory alkaline phosphatase (SEAP) as a transcription reporter in response to the NF-kB activity. Melanogenesis inhibitors such as niacinamide, kojic acid, hydroquinone, resorcinol, arbutin and glycolic acid were pre-incubated with transfectant HaCaT cells for 3 h and then irradiated with ultraviolet B (UVB). Of the melanogenesis inhibitors tested, kojic acid (IC50 = 60 μM) was found to be the most potent inhibitor of UVB-upregulating NF-κB activation in transfectant HaCaT cells, which is followed by niacinamide (IC50 = 540 μM). Especially kojic acid and niacinamide effectively lowered NF-κB binding as measured by the electrophoretic mobility shift assay. Furthermore, these two inhibitors remarkably reduced the secretion level of IL (interleukin)-6, one of the melanotrophic factors, triggered by UV radiation of the HaCaT cells. These observations suggest that melanogenesis inhibitors working at the in vivo level might act partially through the modulation of the synthesis of melanotrophic factors in keratinocytes. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10544
in IFSCC MAGAZINE > Vol. 7, N° 1 (01-02-03/2004) . - p. 39-45[article]Réservation
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Code-barres Cote Support Localisation Section Disponibilité 003882 - Périodique Bibliothèque principale Documentaires Disponible
Titre : Potential cosmetic applications of reconstructed epidermis Type de document : texte imprimé Auteurs : M. Regnier, Auteur ; C. Duval, Auteur ; R. Schmidt, Auteur Année de publication : 1999 Article en page(s) : p. 51–58 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Epiderme reconstruit' Kératinocytes Mélanocytes 'Cellules de Langerhans Index. décimale : 668.5 Parfums et cosmétiques Résumé : Various models of reconstructed epidermis already provide useful tools for safety and efficacy assessment of cosmetic products. However, the majority of these in vitro models are composed of keratinocytes only. Recently, the introduction of melanocytes into epidermal reconstructs has considerably enlarged their field of application. Depending on the melanocyte donor, the different phototypes (I–VI) as well as the racial specific pigmentation, caucasian, Asiatic or black epidermis can be reproduced in vitro. The reconstructed pigmented epidermis allows the evaluation of modulators of melanogenesis such as the depigmenting agent kojic acid. In contrast to conventional melanocyte cultures, the pigmented reconstructed epidermis is air-exposed and covered, as in vivo, with a stratum corneum. This allowed us to evaluate the effect of UV-irradiations on the epidermis and its protection by topically applied sunscreens. The introduction of resident epidermal Langerhans cells into the reconstructed epidermis remained an important challenge. We succeeded by seeding blood derived CD34+ hematopoietic progenitors onto a reconstructing epidermis composed of keratinocytes and melanocytes. The resulting pigmented epidermis shows melanocytes in the basal layer and resident epidermal Langerhans cells suprabasally. As in normal skin, the melanocytes transfer melanin to the neighboring keratinocytes, and the Langerhans cells express major histocompatibility complex class II molecules, CD1a antigen and Birbeck granules. This reconstructed epidermis, comprising for the first time the three major epidermal cell types, has the potential to serve in the near future as a predictive model for immuno-pharmaco-toxicological in vitro studies. DOI : 10.1046/j.1467-2494.1999.183571.x En ligne : https://onlinelibrary.wiley.com/doi/10.1046/j.1467-2494.1999.183571.x Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26504
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 21, N° 1 (02/1999) . - p. 51–58[article]Exemplaires
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