[article]
| Titre : |
Nontraditional use of the biocide DBNPA in coatings manufacture |
| Type de document : |
texte imprimé |
| Auteurs : |
Mary C. Chervenak, Auteur ; Gerald B. Konst, Auteur ; William R. Schwingel, Auteur |
| Année de publication : |
2005 |
| Article en page(s) : |
p. 38-42 |
| Note générale : |
Bibliogr. |
| Langues : |
Américain (ame) |
| Index. décimale : |
667.9 Revêtements et enduits |
| Résumé : |
DBNPA is a powerful biocide with two unique properties: it kills micro-organisms immediately upon addition and it degrades rapidly. Although DBNPA is compatible with many chemical classes, including oxidizing agents, it will react readily with nucleophilic agents and sulfur-containing reducing agents. The facile reaction of DBNPA with sulfur-containing nucleophiles common to microorganisms, such as glutathione or cysteine, is the basis of its mode of antimicrobial action. DBNPA is therefore not a typical oxidizing or halogen-releasing biocide. Unlike other thiol-reactive biocides, its action is such that thiol-based amino acids, like cysteine, are oxidized beyond the formation of disulfide species.5 This reaction irreversibly disrupts the function of cell-surface components, interrupting transport across cell membranes, and inhibiting key biological functions. DBNPA degrades rapidly by both nucleophilic and hydrolytic pathways to relatively nontoxic products. The rate of hydrolysis of DBNPA is strongly pH-dependent: at pH 6.0 and 25°C, the DBNPA molecule has a half-life of 155 hours (about 6.5 days), but at pH 8.0 and 25°C, its half-life is about two hours. The ultimate degradation products of DBNPA are ammonia, carbon dioxide, and bromide ion.
DBNPA, when formulated as a 20% solution in water and polyethylene glycol, is completely miscible with water and readily disperses upon introduction into a water-based system. The DBNPA molecule begins functioning as an antimicrobial agent immediately upon introduction into a system; the rate of this activity is not affected by pH and antimicrobial control is usually achieved before complete degradation occurs. The combination of instantaneous antimicrobial activity and rapid chemical breakdown makes DBNPA a cost-effective biocide that swiftly degrades in the environment. |
| En ligne : |
https://drive.google.com/file/d/11cGJnrmo88Yjj2QvV_Tnq9jlsAhQkqoY/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=5529 |
in COATINGS TECH > Vol. 2, N° 13 (02/2005) . - p. 38-42
[article]
|
Aller sur edunet
Accueil
Ajouter le résultat dans votre panier Affiner la rechercheNontraditional use of the biocide DBNPA in coatings manufacture / Mary C. Chervenak in COATINGS TECH, Vol. 2, N° 13 (02/2005)
