| Titre : |
Sunshine in a bottle : Harnessing the power of persicaria tinctoria extract for radiant skin and enhanced well-being |
| Type de document : |
texte imprimé |
| Auteurs : |
Morgane de Tollenaere, Auteur ; Anaïs Durduret, Auteur ; Emilie Chapuis, Auteur ; Jessy Martinez, Auteur ; Bénédicte Sennelier-Portet, Auteur ; Amandine Scandolera, Auteur ; Romain Reynaud, Auteur |
| Année de publication : |
2024 |
| Article en page(s) : |
p. 8-14 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Bien-être
Cosmétiques
Dermo-cosmétologie
Etudes cliniques
Evaluation
Extraits de plantes:Extraits (pharmacie)
Mélamine -- Synthèse
Neurocosmétique
Peau -- Soins et hygiène
Persicaria tinctoria
Vitamine D -- Synthèse
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Givaudan Active Beauty has developed an ingredient derived from Persicaria tinctoria, a botanical species of the buckwheat family, with the purpose of replicating the positive effects of sunlight. This innovative extract is designed to promote well-being and stimulate tanning without the need for actual sun exposure. Its main focus is to address the mood changes that occur during seasonal transitions, particularly in winter, when there is limited sun exposure and lower levels of vitamin D3. Givaudan conducted extensive research using in vitro models of keratinocytes and melanocytes that were co-cultured and ex vivo models to evaluate the pro-pigmenting activity. β-endorphin and oxytocin were quantified in the culture medium of keratinocytes stimulated with the extract. Vitamin D3 production was measured after the grinding of skin explants treated for several days with Persicaria tinctoria extract.
Finally, clinical trials were conducted to demonstrate the extract’s ability to enhance mood and improve skin health. Corroborating the hypothesis that the extract can act as a “molecular sun”, the results demonstrated its ability to significantly increase melanin content up to +66% in skin explants in comparison with placebo cream. In keratinocytes stimulated with the extract, β-endorphins increased by +43% and oxytocin by +229%. Vitamin D3 production rose significantly to 86.5%. A positive effect on mood was confirmed in vivo in a panel of volunteers who fill specific questionnaires and said they observed a significant reduction of tiredness and an increase of affectionate mood state, leading to an overall improvement of low mood.
In summary, Persicaria tinctoria extract offers myriad of sun-mimicking benefits including tanning activity, mood-enhancement and vitamin D3 stimulation. This can help address vitamin D deficiency and support overall skin and body health, particularly in regions and seasons with limited sunlight. |
| Note de contenu : |
- MATERIALS AND METHODOLOGY : Evaluating pro-pigmenting activity in vitro - Evaluating pro-pigmenting activity on skin explants using Fontana Masson's staining - Enhanced positive mood and well-being : Quantifying beta-endorphin release in keratinocytes - Enhancement of positive mood and well-being : Quantifying oxytocin release in keratinocytes - Enhanced positive mood and well-being : Quantifying vitamin D3 in skin explants - Clinical evaluation of the mood-boosting properties of Persicaria tinctoria extract
- RESULTS : Sun-like effects of Persicaria tinctoria extract - Clinical study on mood-enhancement - Tiredness reduction, improved mood and improved feelings of affection |
| En ligne : |
https://drive.google.com/file/d/1tYgaB-ZUiZkIvrNENqI-gX9rwJnHe0XL/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=41326 |
in SOFW JOURNAL > Vol. 150, N° 7-8 (07-08/2024) . - p. 8-14
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