Cosmetic UV filters in the environment-state of the art in EU regulations, science and possible knowledge gaps / Sascha Pawlowski in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 45, N° S1 (10/2023)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 45, N° S1 (10/2023) . - p. 52-66 Titre : Cosmetic UV filters in the environment-state of the art in EU regulations, science and possible knowledge gaps Type de document : texte imprimé Auteurs : Sascha Pawlowski, Auteur ; Laura Henriette Luetjens, Auteur ; Alina Preibisch, Auteur ; Stephanie Acker, Auteur ; Mechtild Petersen-Thiery, Auteur Année de publication : 2023 Article en page(s) : p. 52-66 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Chimie industrielle -- Législation -- Pays de l'Union européenne cosmétiques -- Produits chimiques Produits antisolaires Règlements de sécurité Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : The aim of this work was to review the principals of environmental hazard and risk assessment (ERA) of cosmetic UV filters registered under EU REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals). Furthermore, effects as obtained from non-standardized testing methods and organisms from scientific literature were compared against the predicted no effect concentrations (PNECs) as derived based on standardized test methods for the various environmental compartments under REACH. - Methods : The REACH dossiers at the ECHA webpage were screened for available information related to basic physico–chemical data (i.e. water solubility, octanol–water partitioning coefficient), PNECs and associated data (data basis, assessment factors (AFs)). Scientific literature was screened for available ecotoxicity data and the adverse effect levels were compared against the derived PNECs under REACH. Current approaches for environmental risk assessments of UV filters were evaluated for its applicability for a direct release scenario. - Results : Under REACH, PNECs were derived for all hazardous UV filters. Although, PNECs were often derived for various environmental compartments (i.e. freshwater, marine water, sediment, soil), results from literature focused on aquatic data. Effects as observed within scientific literature matches in principle with the hazardous profile of the UV filters. Effects levels both on the acute and the chronic toxicity as retrieved from the non-standardized test organisms (literature) were above the derived PNECs under REACH. Currently, ERAs performed for cosmetic UV filters under REACH are solely tonnage driven and thus do not fully capture the use in sunscreens and associated leisure activities. - Conclusion : Existing EU REACH regulation is considered as sufficient to evaluate the environmental safety of UV filters used in sunscreens. To cover the direct release of UV filters due to various leisure activities into the aquatic freshwater and marine environment, an additional application-based ERA is considered necessary. Note de contenu : - MATERIALS AND METHODS : Review of information requirements for UV filters under REACH - Extraction of relevant information from REACH dossiers - Extraction of relevant information from literature review - Comparison of effect levels from non-standardized test organisms with derived PNECs under EU REACH - RESULTS : Review of information requirements for UV filters and principles of environmental risk assessments (ERAs) under REACH - Review of relevant information related to the environmental safety of UV filters within EU REACH - Review of scientific literature - Comparison of REACH derived PNECs with toxicity levels from non-standardized tests - Table 1 : Overview of investigated UV filters and relevant physical–chemical properties - Table 2 : Overview of principal environmentally related data requirements for substances such as UV filters used in sunscreens under REACH - Table 3 : Freshwater : Predicted no effect concentrations (PNECfreshwater) from the REACH registration dossier of UV filters and most sensitive data on various organisms from literature (acute and chronic) - Table 4 : Marine water: Predicted no effect concentrations (PNECmarine water) from the REACH registration dossier of UV filters and most sensitive data on various organisms from literature (acute and chronic) DOI : https://doi.org/10.1111/ics.12898 En ligne : https://onlinelibrary.wiley.com/doi/epdf/10.1111/ics.12898 Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40251 [article]

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