Results from an extended study on the reliability of a questionnaire for the diagnosis of sensitive skin: Confirmations and improvements / Alessandro Borghi in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 45, N° 1 (02/2023)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 45, N° 1 (02/2023) . - p. 108-115 Titre : Results from an extended study on the reliability of a questionnaire for the diagnosis of sensitive skin: Confirmations and improvements Type de document : document électronique Auteurs : Alessandro Borghi, Auteur ; Fabrizio Guarneri, Auteur ; Leda Montesi, Auteur ; Lucrezia Pacetti, Auteur ; Irene Donelli, Auteur ; Monica Corazza, Auteur Année de publication : 2023 Article en page(s) : p. 108-115 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Barrière cutanée Dermatologie Lactique, Acide L'acide lactique est un acide organique qui joue un rôle dans divers processus biochimiques. Un lactate est un sel de cet acide. Contrairement à ce que peut laisser penser son nom, l'acide lactique n'est pas présent uniquement dans le lait, mais également dans le vin, certains fruits et légumes, et dans les muscles. L'acide lactique est un acide alpha hydroxylé, sa formule chimique est C3H6O3 et sa structure se reflète dans son nom systématique, l'acide 2-hydroxypropanoïque. Questionnaires Sensibilité cutanée Statistique Test de la piqure (dermatologie) Tests de sécurité Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : A recently proposed self-assessment questionnaire aimed at diagnosing sensitive skin provided promising results in a relatively small population. The main objectives were: (i) to assess the reliability of the aforementioned questionnaire in a larger population and verify the cut-off score previously found to predict skin sensitivity (defined as positivity to LAST, lactic acid stinging test) and (ii) to define a formula that yields the probability of a positive LAST result. - Methods : Adult volunteers were included in this observational, cross-sectional, extended study. Both LAST-positive subjects, who were considered as having sensitive skin (‘patients’) and negative ones (‘controls’) completed the questionnaire, which concerned sensitivity to possible triggers of unpleasant skin sensations in real life. A cumulative score (questionnaire-based skin sensitivity score, 0–10) was calculated from the sum of all items. - Results : Three hundred and sixty-four subjects were enrolled, 214 patients and 150 controls. The mean questionnaire-based skin sensitivity score was significantly higher among patients than controls. Using two different methods, cut-off values of 4 and 5 were defined for the identification of LAST-positive subjects, with 76.6% and 72.8% accuracy, respectively. Scores below 4 or above 5 showed a high (80% or better) negative or positive predictive value, respectively. The coefficients found that in multivariate analysis for each questionnaire item, gender and age allowed us to calculate the probability of LAST positivity with higher precision taking into account the 'relative weight' of each factor. - Conclusion : With small variations in the results, the self-assessment questionnaire confirmed its reliability for diagnosing sensitive skin in clinical practice. Note de contenu : - MATERIAL AND METHODS : Study design and population - Statistical analysis - RESULTS : Patients' characteristics - Self-assessment - Questionnaire reliability - Table 1 : Demographic characteristics of the study subjects who claimed having/not having sensitive skin - Table 2 : Self-assessed skin sensitivity scores (VAS, 0–10) of patients and controls, grouped (i) by sex and (ii) by their answer to the question ‘Do you think that you have sensitive skin ?’ - Table 3 : Reaction to potentially triggering stimuli : Mean cumulative scores of patients and controls, grouped (i) by sex and (ii) by their answer to the question ‘Do you think that you have sensitive skin ?’ - Table 4 : Sensitivity, specificity, positive and negative predictive values and accuracy of the possible cut-off values of questionnaire-assessed skin sensitivity score for the correct diagnosis of sensitive skin, i.e. positivity to the LAST - Table 5 : Multivariate logistic regression showing the relevance of different variables in determining the positive result to LAST DOI : https://doi.org/10.1111/ics.12817 En ligne : https://drive.google.com/file/d/1JfUKUOmmlrpt44NqriXQ4IfrPyn937J7/view?usp=share [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=38824 [article]

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