Facial skin ageing : Key concepts and overview of processes / David Zargaran in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 44, N° 4 (08/2022)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 44, N° 4 (08/2022) . - p. 414-420 Titre : Facial skin ageing : Key concepts and overview of processes Type de document : document électronique Auteurs : David Zargaran, Auteur ; Florence Zoller, Auteur ; Alexander Zargaran, Auteur ; Tim Weyrich, Auteur ; Afshin Mosahebi, Auteur Année de publication : 2022 Article en page(s) : p. 414-420 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Dermo-cosmétologie Hydratation Peau -- Anatomie Peau noire -- Physiologie Produits antisolaires Protection contre le rayonnement ultraviolet Vieillissement cutané Visage -- Soins et hygiène Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Introduction : The face is a cosmetically sensitive region where the process of ageing is most clearly manifested. With increased focus on anti-ageing and longevity, more anti-senescent treatments are being proposed despite limited evidence. This study outlines the pathways and mechanisms underpinning the biological process of ageing in the face. - Methods : Comprehensive searches of MEDLINE, EMBASE, Cochrane Library and CINAHL from inception to 2020. Inclusion criteria included all empirical human research studies specific to facial ageing features, written in the English language. Results : A total of 65 papers met inclusion criteria for analysis. Pathways were subdivided into intrinsic and extrinsic senescence mechanisms. Intrinsic pathways included genetics, generation of reactive oxygen species and hormonal changes. Extrinsic pathways included photoageing and damage to skin layers. The combined intrinsic and extrinsic pathway alterations result in wrinkles, higher laxity, slackness and thinning of the skin. Skin functions such as barrier immune function, wound healing, thermoregulation and sensory function are also impaired. - Conclusion : The ageing process is unique to the individual and depends on the interplay between an individual's genetics and external environmental factors. Through understanding the molecular and cellular mechanisms, an appreciation of the consequent structural and functional changes can be achieved. Based on this knowledge, further research can focus on how to slow or impede the ageing process and identify specific targets to develop and evolve new treatment strategies. Note de contenu : - BACKGROUND : Genetic alterations - Reactive oxygen species (ROS) and free radicals - Hormones - SKIN AGEING : Extracellular matrix components - Photoageing - Epidermis - Dermo-epidermal junction - Dermis - FAT, CARTILAGE, BONE AND MUSCULAR TISSUE : Fat - Cartilage and bone - Muscles DOI : https://doi.org/10.1111/ics.12779 En ligne : https://drive.google.com/file/d/19oMiISUsdI1aNFzafsHYvjv8ZqQdzP_l/view?usp=shari [...] Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=38141 [article]

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