| Titre : |
Blue light and premature skin aging - New in vivo test method |
| Type de document : |
texte imprimé |
| Auteurs : |
Dorothée Dähnhardt, Auteur ; A. V. Seebach, Auteur ; S. Dähnhardt-Pfeiffer, Auteur ; Doerte Segger, Auteur |
| Année de publication : |
2022 |
| Article en page(s) : |
p. 28-32 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Dermatologie
Etude in vivo
Lumière artificielle -- Effets physiologiques
Lumière bleue
Vieillissement cutané
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The harmful effects of blue light rays on the skin are increasingly becoming the focus of the cosmetics industry and consumers. So far, only a few test methods for measuring the effects of blue light on the skin have been described in the literature. Direct detection methods that show the immediate effects of blue light on the collagen network of the skin are still missing. In the work presented here, a new test method for measuring the effect of blue light on the skin is presented.
The skin of volunteer subjects was irradiated with a light source with a narrow emission spectrum and low-dose blue light (6 J/cm2).
Before irradiation, and 1 hour respectively 24 hours after irradiation, we were able to detect the increase in MMP-1 concentration and the decrease in type 1 procollagen in the blister fluid of the suction blisters. We were able to visualize the collagen network with the help of scanning electron microscopy (SEM) on the underside of the suction blister roofs and quantitatively evaluate it with the help of an image analysis. Here, too, after blue light treatment, there was an increasing degradation of the collagen fibers as well as a decrease in the length of the collagen strands.
The presented study can be used as an effective in vivo test method for products that want to reduce the negative effects of blue light on the skin and reduce premature skin aging. |
| Note de contenu : |
- Subjects and study design
- Blue light irradiation
- Generation of suction blisters
- Determination of procollagen 1 and MMP-1
- Scanning electron microscopy and image analysis |
| En ligne : |
https://drive.google.com/file/d/1cwcyn2Xjr8yBCeuXgN7aDj2IN9MX-wql/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37102 |
in SOFW JOURNAL > Vol. 148, N° 1/2 (01-02/2022) . - p. 28-32
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