| Titre : |
The study of a palmitoyl oligopeptide complex : a 3D anti-aging theory |
| Type de document : |
texte imprimé |
| Auteurs : |
Lu Yi-Na, Auteur ; Zhou Chun-Xia, Auteur ; Yang Ya-Di, Auteur ; Zhang Heng, Auteur ; Tian Jun, Auteur |
| Année de publication : |
2021 |
| Article en page(s) : |
p. 32-36 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antiâge
Antiâge:Antirides
Cosmétiques
Dermo-cosmétologie
Peau -- Soins et hygiène
Peptides
Statistique
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Skin is a multifunctional organ but, alongside every other organ system, is subject to both intrinsic and extrinsic aging. Whilst both ageing processes are associated with phenotypic changes in cutaneous cells, the major functional manifestations of ageing occur as a consequence of structural and compositional remodeling of normally long-lived dermal extracellular matrix proteins, flattened dermal-epidermal junction (DEJ), and weaker epidermal function. Many researchers revealed that dermal fibroblast which mainly synthesis the collagen and elastin in dermis, while the epidermal keratinocyte and DEJ are lesser described, especially for peptides. A new palmitoyl oligopeptide complex PTC, which consists of hydrolyzed collagen and oligopeptide, was identified in both keratinocyte and fibroblast, and finally verified in human skin. All data suggest PTC had a 3D theory against skin aging: from epidermal keratinocyte to dermal fibroblast, especially containing the structural proteins of DEJ. |
| Note de contenu : |
- METHODOLOGY : PTC preparation - Maintenance of cells - Cell proliferation experiments - DEJ proteins ELISA detection - Dermal proteins detection - TGF-β1 ELISA detection - Skin wrinkles evaluation - Statistical analysis
- RESULTS AND DISCUSSION : PTC improves the proliferation of NHEK and HDF-a - PTC improves the expression of DEJ proteins - PTC induced the synthesis of collagens and ECM proteins - PTC upregulated TGF-β1 expression - PTC reduced the wrinkles and roughness of human skin |
| En ligne : |
https://drive.google.com/file/d/1y2i5niHSEdMEDs95I0fBe-Wjgmfrv45m/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35973 |
in SOFW JOURNAL > Vol. 147, N° 6 (06/2021) . - p. 32-36
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