| Titre : |
Effects of petrolatum, a petrolatum depositing body wash and a regular body wash on biomarkers and biophysical properties of the stratum corneum |
| Type de document : |
document électronique |
| Auteurs : |
Karl Wei, Auteur ; Ching Stella, Auteur ; Kenneth Wehmeyer, Auteur ; Jeremy Christman, Auteur ; Amy Altemeier, Auteur ; Russell Spruell, Auteur ; Rohan Wimalasena, Auteur ; Gina Fadayel, Auteur ; R. Randall Wickett, Auteur |
| Année de publication : |
2021 |
| Article en page(s) : |
p. 218-224 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Acide pyrrolidone carboxylique
Cosmétiques
Facteur naturel d'hydratation
Gel douche
Peau -- Soins et hygiène
Perte insensible en eau
Protéines
Statistique
Vaseline
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Background : An important trend in the personal care industry involves the development of body wash products that not only clean the skin without damage but deposit conditioning ingredients to improve skin barrier function.
Objective : The objective of this study was to develop skin biomarker measures to quantify the treatment effects of body wash products.
Methods : We employed analysis of structural proteins (keratin 1,10,11 and involucrin), a natural moisturizing factor (pyrrolidone carboxylic acid) and an inflammatory mediator (IL-1ra/IL-1α) from adhesive discs with dry skin grading, TEWL and capacitance measurements to compare the effects of direct application of petrolatum, a high petrolatum depositing body wash, and a regular body wash on dry leg skin in a standard leg-wash treatment protocol.
Results : High depositing body wash and petrolatum had positive effects on stratum corneum barrier function as judged by biomarker analysis, biophysical measurements and skin grading compared to the regular body wash product.
Conclusions : The results clearly indicate that a combination of biomarker and biophysical property measurements is effective for determining the skin benefits of moisturizing body wash products. |
| Note de contenu : |
- Subjects - Treatment protoco
- Biophysical measurements and SC sampling
- D-squame analysis scheme
- Statistical methods
- Table 1. Skin measurements at baseline (base size n = 45)
- Table 2. Direction of changes in biophysical and biomarker parameters |
| DOI : |
https://doi.org/10.1111/ics.12684 |
| En ligne : |
https://drive.google.com/file/d/161WS2KbJbVsv7-tFcoghUsu078LyZdoA/view?usp=shari [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35765 |
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 43, N° 2 (04/2021) . - p. 218-224
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