| Titre : |
Sphingolipid identification and skin barrier recovery capacity of a milk sphingolipid-enriched fraction (MSEF) from buttermilk powder |
| Type de document : |
document électronique |
| Auteurs : |
K. Lee, Auteur ; S. Kim, Auteur ; A. Kim, Auteur ; H. J. Suh, Auteur ; K.-B. Hong, Auteur |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 270-276 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Barrière cutanée
Evaluation
Hydratation
Ingrédients cosmétiques
Lait et constituants
Peau -- Soins et hygiène
Produits hydratants
Sphingolipides
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
- Objective : In this study, we isolated the milk sphingolipid-enriched fraction (MSEF) of sweet buttermilk powder and conducted a clinical trial for evaluating its efficacy in skin barrier recovery.
- Methods : Milk sphingolipid-enriched fraction was isolated via solvent extraction of buttermilk powder, and further concentrated by removing the phospholipids and neutral lipids. A cream containing 1% MSEF was used during clinical trials to assess for water holding and skin barrier recovery capacities.
- Results : The main components of the MSEF were sphingomyelin, glucosylceramide and lactosylceramide, confirmed by TLC, HPLC, MS and NMR. The MSEF cream-treated group had a significantly higher (P < 0.05) water holding capacity, compared with the base cream (vehicle) group. Compared with that in the base cream group, transepidermal water loss (TEWL) recovery increased in the presence of the sphingolipid-containing MSEF cream (MSEF group), with a significant difference (P < 0.05) recorded on day 14.
- Conclusion : The MSEF cream contributed to improving the water holding capacity and skin barrier recovery of damaged skin. Therefore, sphingolipid-containing MSEF can be useful for strengthening or repairing skin barrier function. |
| Note de contenu : |
- MATERIALS AND METHODS : Materials - Production of milk sphingolipid-enriched fraction - Clinical tests - Determination of three main MSEF sphingolipids - Preparation of 1% cream for clinical trial - Isolation of 3 main sphingolipid compounds - Study protocol - Skin assessments - Statistical analyses
- RESULTS : Analyses of sphingolipids in MSEF - Clinical trials for evaluating the effect of MSEF cream on skin hydration and skin barrier function
- Table 1 : Ingredients and composition of base cream and MSEF cream
|
| DOI : |
https://doi.org/10.1111/ics.12612 |
| En ligne : |
https://drive.google.com/file/d/1UPg37Gy-xB7w93UVj_V2bWw3V3d7FZ7y/view?usp=shari [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35274 |
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 42, N° 3 (06/2020) . - p. 270-276
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