Alginate microparticles as carriers for the UV filter 2-ethylhexyl 4-methoxycinnamate : Influence on photostability / J. Duarte in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 41, N° 6 (12/2019)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 41, N° 6 (12/2019) . - p. 585-593 Titre : Alginate microparticles as carriers for the UV filter 2-ethylhexyl 4-methoxycinnamate : Influence on photostability Type de document : texte imprimé Auteurs : J. Duarte, Auteur ; Isabel F. Almeida, Auteur ; M. Costa, Auteur ; E. S. Da Silva, Auteur ; J. L. Faria, Auteur ; José M. Sousa Lobo, Auteur ; Paulo Jorge Cardoso Costa, Auteur ; S. Scalia, Auteur Année de publication : 2019 Article en page(s) : p. 585-593 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Alginate de sodium L'alginate de sodium ou polymannuronate sodique, de formule NaC6H7O6 est un additif alimentaire (E401) utilisé dans les boissons, constitué d’alginate et de sodium. Il se présente sous forme de poudre blanche à blanc crème, inodore et sans saveur, très soluble dans l'eau. C'est une longue molécule extraite d'algues brunes, constituée d'unités de glucides reliées ensemble pour former une chaîne. Cosmétiques Encapsulation Octyl méthoxycinnamate Particules (matières) Peau -- Soins et hygiène Photostabilité Produits antisolaires Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : The organic ultraviolet UVB filter 2-ethylhexyl 4-methoxycinnamate (EHMC) was encapsulated in microparticles (MPs) of sodium alginate and co-loaded with vitamin E (Vit.E) by an extrusion process using an aerodynamically assisted jetting (AAJ) methodology. The aim was to assess the effect of encapsulation concerning UVB filter release from the MPs and its photochemical stability. - Methods : The EHMC photostability was analysed by exposing the samples (both MPs in aqueous dispersion and incorporated in a cream preparation) during 1 h to simulated solar light. For the MPs (empty-MP, EHMC-MP and EHMC + Vit.E-MP), the morphology and size were characterized ; while in the case of the encapsulated samples, the amount of EHMC-loading was determined. The release of EHMC was evaluated by adding EHMC-MP or EHMC + Vit.E-MP to 65% ethanol in water under mechanical stirring at 32°C. - Results : All MPs showed a homogeneous size distribution with a median of 90.5 ± 2.5 µm for EHMC-MP and 70.4 ± 1.14 µm for EHMC + Vit.E-MP. The encapsulation efficiency was 92.9% and 99.4% for EHMC-MP and EHMC + Vit.E-MP, respectively. The observed release from the MPs was lower than the dissolution of the pure UV filter. EHMC-MP and EHMC + Vit.E-MP were successfully incorporated into a cream formulation, with no evidence of phase separation or colour modification. Upon simulated light exposure, the photoisomerization/phototransformation of EHMC encapsulated in MPs and Vit.E-MP decreased as compared to free EHMC, both in aqueous dispersion and as a cream. The conformational ratio of the isomers (Z-/E-EHMC) was found to be the lowest in the presence of Vit.E. - Conclusion : This work demonstrates that use of these alginate microparticulate carriers could enhance the effectiveness of sunscreen preparations containing this UVB filter. Note de contenu : - MATERIALS AND METHODS : materials - Microparticles production - Microparticles freeze drying - EHMC assay - Microparticles characterization - Cream preparation - Photostability - Statistical analysis - RESULTS AND DISCUSSION : Microparticles characterization DOI : 10.1111/ics.12578 En ligne : https://drive.google.com/file/d/1vdfA1ng0cfaEgKvHauMvWo7OC225Zq7X/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=33667 [article]

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