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Reduction of DNA damage by nicotinamide after reactive oxygen species treatment / S. C. Chen in IFSCC MAGAZINE, Vol. 5, N° 1 (01-02-03/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 1 (01-02-03/2002) . - p. 3-6 Titre : Reduction of DNA damage by nicotinamide after reactive oxygen species treatment Type de document : texte imprimé Auteurs : S. C. Chen, Auteur ; Y. Takasli, Auteur ; Y.-C. Chen, Auteur ; T. H. Tsai, Auteur ; C. H. Hu, Auteur ; W. R. Lee, Auteur Année de publication : 2002 Article en page(s) : p. 3-6 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : ADN -- Réparation Apoptose Nicotinamide Peroxyde d'hydrogène Le peroxyde d'hydrogène (H2O2), communément appelé eau oxygénée ou encore perhydrol (appellation industrielle), est un composé chimique liquide et visqueux, aux puissantes propriétés oxydantes (il est aussi réducteur). C'est donc un agent blanchissant efficace qui sert de désinfectant et (à haute concentration) d'oxydant ou monergol dans les fusées spatiales. Rayonnement ultraviolet Tags : Nicotinamide  'Ultraviolet  C'  (UVC)  'OPeroxyde  d'hydrogène'  (ROS)'  'Dommage  de  l'ADN''  Apoptose  '8-hydroxy-2'-deoxyguanosine(8-OhdG)' Index. décimale : 668.5 Parfums et cosmétiques Résumé : We investigated whether nicotinamide acts as a preventive agent of apoptosis induced by H2O2 and UVC irradiation in skin cells including keratinocyte HaCat and NIH3T3 cells. In this study, both H2O2 (450μM) and UVC (40J/m2) irradiation-induced cell death were detected by MTT assay, and nicotinamide showed the dose dependent inhibition on H2O2 and UVC induced cell death. Morphological study by microscopic observation showed that H2O2 or UVC induced cellular morphological changes including appearence of rounded cells or swelling cells, characteristic og apoptosis. In the presence of nicotinamide, H2O2 and UVC induced morphological changes were attenuated significantly. Prevention of cells from H2O2 and UVC induced cell death was asociated with decrease of apoptotic bodies by flow cytometry analysis and attenuation of the appearance of DNA ladders by DNA electrophoresis. Induction of p53 protein was detected in H2O2-treated NIH3T3 cells and nicotinamide suppressed its increase. However, bcl-2, bax and α-tubulin proteins were remained unchanged. ROS have been demonstrated to be involved in the H2O2 and UVC induced apoptosis. In this study, H2O2 or UVC irradiation increase intracellular peroxide levels detected by DCHF-DA assay and fluorescent microscopic observation, and nicotinamide blocked the peroxide level induced by H2O2 or UVC irradiation. Decrease of H2O2 or UVC-induced 8-OH dG in DNA was also detected in nicotinamide trated cells. The results of present study firstly demonstrated that nicotinamide prevented cells from H2O2 and UVC irradiation induced apoptosis through suppression ROS production, p53 elevation and 8-OH dG formation. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10656 [article]

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Effect of alkyl substitution on styling and conditioning properties of co(Vinyl pyrrolidone - DMAPMA - DMAPMA+ - C12H25Cl-) / J. Jachowicz in IFSCC MAGAZINE, Vol. 5, N° 1 (01-02-03/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 1 (01-02-03/2002) . - p. 9-17 Titre : Effect of alkyl substitution on styling and conditioning properties of co(Vinyl pyrrolidone - DMAPMA - DMAPMA+ - C12H25Cl-) Type de document : texte imprimé Auteurs : J. Jachowicz, Auteur ; R. Chuang, Auteur ; Roger L. McMullen, Auteur ; T. Winkler, Auteur ; T.. Kirsch, Auteur ; X. Yu, Auteur Année de publication : 2002 Article en page(s) : p. 9-17 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Cationic  polymer'  'Hydrophobic  modification'  Cosmetics  'Surface  tension'  'Hair  styling'  Conditioning Index. décimale : 668.5 Parfums et cosmétiques Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10661 [article]

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Sensory evaluation of moisturizing creams : combination of descriptive analysis panel test and preference test / So-Yeon Sim in IFSCC MAGAZINE, Vol. 5, N° 1 (01-02-03/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 1 (01-02-03/2002) . - p. 19-23 Titre : Sensory evaluation of moisturizing creams : combination of descriptive analysis panel test and preference test Type de document : texte imprimé Auteurs : So-Yeon Sim, Auteur ; Soo-Jeong Jeong, Auteur ; Bo-Kyoung Sun, Auteur ; Seong-Joon Moon, Auteur ; Ih Seop Chang, Auteur Année de publication : 2002 Article en page(s) : p. 19-23 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Sensory  evaluation'  'Moisturizing  cream'  'Trained  panel'  Consumer  Preference  'Descriptive  analysis'  'Preference  testing  and  principal  component Index. décimale : 668.5 Parfums et cosmétiques Résumé : The two most important factors that are perceived by consumers using cosmetic products are the biological or clinical effect and the sensorial effect. For repeated use of a product, its skin feel must be pleasant and comfortable to the user. As the skin feel of a product depends on the user’s sensation, the sensory evaluation is indispensable to measure and analyze its characteristics. Therefore, quantitative and descriptive sensory evaluation measuring the intensity of the characteristics and consumer’s preference evaluation are both required, and its desirable to correlate them. We selected women through discriminative and descriptive tests to form a trained panel. They described the skin feel using various creams and emulsions, and sorted out the terms through discussion to decide the evaluation terminology and the definition of each term. Then, they were trained to remember the intensities of the reference materials’ characteristics. Under the same test condition, moisturizing creams were tested by the same test method. The statistical analysis of the collected data showed that the principal components of the feel of these moisturizing creams were residuary factor and spreadability factor, and according to the results, the products were positioned in a 2-dimensional space. We also selected several creams among the tested products to run a preference test by consumers of various skin types and ages. As a result, we subdivided the preferred skin feel of the moisturizing cream according to the skin type an the age of the consumer. With the descriptive sensory evaluation and the preference test results, we proposed the desirable skin feel of the moisturizing cream corresponding to the consumers’ skin type and age. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10662 [article]

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Lipid analysis and transepidermal water loss in snakes / Nicole Widler in IFSCC MAGAZINE, Vol. 5, N° 1 (01-02-03/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 1 (01-02-03/2002) . - p. 24-29 Titre : Lipid analysis and transepidermal water loss in snakes Type de document : texte imprimé Auteurs : Nicole Widler, Auteur ; Andreas Sigrist, Auteur ; Frank M. Gafner, Auteur Année de publication : 2002 Article en page(s) : p. 24-29 Note générale : Bibliogr. Langues : Anglais (eng) Tags : Analysis  Aridity  'Skin  lipids'  Reptiles  Snakes  'Transepidermal  water  loss' Index. décimale : 668.5 Parfums et cosmétiques Résumé : The lipids of 101 snake sheddings from 32 different species kept at Pentapharm's serpentarium were extracted and analized by HPLC/LSD (light scattering detection) and TLC. The snake shadding extracts were compared with those of human stratum corneum. As revealed by HPLC/LSD analysis, the lipids from the various snake species and from humans are qualitatively not very different. The greatest differences could be observed quantitatively in the neutral lipids such as cholesterol. Main components are cholesterol, fatty acids, triglycerides, glycoceramides and phospholipids. The TLC analysis indicated that the extracts differ above all in the composition of neutral lipids, in contrast to polar lipids that do not show many differences. The transepidermal water loss (TEWL) of 19 different snake species was measured for the first time, according to our knowledge, directly in-vivo using a Tewameter. The results show that undisturbed snakes have a considerably lower TEWL than a stressed common lancehead ( Bothrops atrox). The results of the lipid analysis as well as the direct in-vivo TEWL measurements did not allow confirmation of the thesis of an inverse correlation between the TEWL of a snake and the aridity of its habitat. The HPLC/LSD analysis of human stratum corneum showed a very similar profile a the chromatograms of the snake sheddings. Our analysis did not allow for differentiation between the various classes of ceramides and other lipids that may account for the differences in percutaneous absorption that have been reported for snake and human skin. But on a group-classification basis, snake sheddings should be taken into account as a simple stratum corneum model considering the ease of appendageal penetration pathways have to be kept in mind. A similar esterase activity in snake sheddings and human skin was described previously. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10663 [article]

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Does asian skin induce significant changes in sun protection factor (SPF) determination comparde to caucasian skin : one of the first in-vivo correlations / E. Camel in IFSCC MAGAZINE, Vol. 5, N° 1 (01-02-03/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 1 (01-02-03/2002) . - p. 31-34 Titre : Does asian skin induce significant changes in sun protection factor (SPF) determination comparde to caucasian skin : one of the first in-vivo correlations Type de document : texte imprimé Auteurs : E. Camel, Auteur ; Lynda Aranaud-Boissel, Auteur ; S Schnebert, Auteur ; Michèle Neveu, Auteur ; S. K. Tan, Auteur ; Jean-Pierre Guillot, Auteur Année de publication : 2002 Article en page(s) : p. 31-34 Note générale : Bibliogr. Langues : Anglais (eng) Tags : 'Asian  skin'  Caucasian  'Skin  color'  Ethnic  differences'  MED  SPF Index. décimale : 668.5 Parfums et cosmétiques Résumé : The aim of this study was compare the SPF of three sunscreens (SPF 6/8-15/20-25/30) and 2 standars ( FDA,COLIPA fla P2), according to COLIPA recommendations, in panels of Asian (Singapore) and Caucasian (France) volunteers. Sixty male and female groups panelists were included in the test: two groups of Asians, defined according their color typology (as measured with a Chromameter: I.T.A.°:28-41° or 41-60°), and one group of Caucasians (I.T.A.°: 41-60°) in order to make a possible correlation with the light colored Asians. Results showed statistically significantly higher SPF in the lighter Asian skin group (I.T.A.°:41-60°) compared to the Caucasian group with similar skin color for the sunscreens with SPF 15 and 30,whereas no significant difference was observed for FDA and COLIPA standards, not for the SPF 6/8 sunscreen. These results show that differences in SPF between Asian and Caucasian skin exist.These differences are clearly present for the high SPF sunscreens and might not be only explained by skin color but also by other internal or external factors affecting skin response to UV. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10673 [article]

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Creating the right environment for innovation / Alan Pearson in IFSCC MAGAZINE, Vol. 5, N° 1 (01-02-03/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 1 (01-02-03/2002) . - p. 37-40 Titre : Creating the right environment for innovation Type de document : texte imprimé Auteurs : Alan Pearson, Auteur ; Jorge Gomes, Auteur Année de publication : 2002 Article en page(s) : p. 37-40 Note générale : Bibliogr. Langues : Anglais (eng) Tags : Innovation  Management  'New  product  development'  Communication  'Team  working'  Projects  Organization  'Reward  systems' Index. décimale : 668.5 Parfums et cosmétiques Résumé : There has been a good deal of research in the field of innovation management. This includes studies at the individual, group and organizational level, which cover a wide range of industries and economic sectors. Based on these studies, the current paper aims to identify and discuss the factors which help to promote innovation within an organization, as well as to examine the implications for management in the Cosmetics and Fragrances industry. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10686 [article]

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