Titre : |
Role of phenolics in the stabilization of collagen |
Type de document : |
texte imprimé |
Auteurs : |
Balaraman Madhan, Auteur ; T. Ramasami, Auteur ; V. Subramanian, Auteur ; Balachandran Unni Nair, Auteur ; Jonnalagadda Raghava Rao, Auteur |
Année de publication : |
2004 |
Article en page(s) : |
p. 157-163 |
Note générale : |
Bibliogr. |
Langues : |
Américain (ame) |
Index. décimale : |
675 Technologie du cuir et de la fourrure |
Résumé : |
Stabilization of the fibrous protein collagen is important in biological and industrial processes. In the present study, three representative phenolic compounds - catechol, resorcinol and pyrogallol have been selected to probe their role in the stabilization of collagen. Hydrothermal stability and the stability against enzyme (collagenase) have been considered as the measures for the stabilization process. It has been found that catechol increased the hydrothermal stability of the collagen fibres by 6.5 °C and also the catechol treated collagen fibres exhibited higher resistance against the degradation by enzyme collagenase. Resorcinol treated collagen fibres exhibited least resistance both against heat and collagenase. Pyrogallol increased the shrinkage temperature of the collagen fibres by 4.5 °C and resisted the activity of collagenase to a considerable extent. Molecular modeling studies have provided clear evidence for the significance of electrostatic and hydrogen bonded interaction in the stabilization of collagen by phenolic compounds. |
En ligne : |
https://drive.google.com/file/d/1I7oW6yeliem0gIk3ZWh0q9dOZZYYYwuw/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=4189 |
in JOURNAL OF THE AMERICAN LEATHER CHEMISTS ASSOCIATION (JALCA) > Vol. XCIX, N° 4 (04/2004) . - p. 157-163