[article]
| Titre : |
Benefits of recombinant type XVII collagen |
| Type de document : |
texte imprimé |
| Auteurs : |
Li Jiaji, Auteur ; Wang Liping, Auteur ; Ji Baihui, Auteur ; Cao Kaijie, Auteur ; Feng Peiying, Auteur ; Fu Shengwei, Auteur |
| Année de publication : |
2024 |
| Article en page(s) : |
p. 100-102 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Collagène
Dermo-cosmétologie
Ingrédients cosmétiques
Peau -- Soins et hygiène
Protéine recombinanteUne protéine hétérologue ou recombinante est une protéine produite par une cellule dont le matériel génétique a été modifié par recombinaison génétique.
Un gène codant une protéine d'intérêt est introduit dans le génome de l'espèce productrice (bactéries, cellules mammifères en culture, animaux transgéniques, etc.). Les protéines recombinantes peuvent être purifiées et utilisées à des fins thérapeutiques, industrielles ou bien encore dans les activités de recherche. (Wikipedia)
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
An important biological protein with unique properties, collagen is used in many fields such as the chemical industry, medicine, food and cosmetics. The collagen sold currently on the market is mainly animal-sourced. However, during the processing of acid, base, or enzymatic extraction methods, a native structure of collagen is basically destroyed, and the protein is severely degraded, resulting in sharply decreased bioactivity.
What is more, animal-sourced collagen is heterogeneous mixture of polypeptides with different sizes, and the significant batch-to-batch difference can lead to unstable qualifies of final products. In addition to the risk of associated infectious diseases brought by animais, such as bovine spongiform encephalopathy, animal-derived collagen may also cause immune hypersensitivity when consumed by humans.
Human collagen type XVII is a transmembrane non-fibroblast collagen, which is a homogeneous trimer composed of three identical α1 (XVII) chains and is divided into three major domains : intracellular, transmembrane, and extracellular domains.
Collagen type XVII is a component of hemidesmosomes in cens and plays an important rote in the interaction between epithelial cells and a basement membrane. It can regulate the cellular adhesion, separation, development, and is important for the differentiation and regeneration of keratinocytes. Besides, maintenance of collagen type XVII in stem cells is critical for orchestrating skin homeostasis and preventing hair follicle ageing. |
| Note de contenu : |
- Amino acid sequence design and chassis cell selection for SRHC type XVII production
- Scale production by biological fermentation with Pichia pastoris of SRHC type XVII
- Efficacy test of SRHC type XVII as a new raw material for cosmetics
- Fig. 1 : Schematic illustration of plasmid used for recombinant expression of SRHC type XVII |
| En ligne : |
https://drive.google.com/file/d/1MlcbwHNVdoWOMrYSxJYRdIGiNZp39HTO/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40902 |
in GLOBAL PERSONAL CARE > Vol. 25, N° 3 (03/2024) . - p. 100-102
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Benefits of recombinant type XVII collagen in GLOBAL PERSONAL CARE, Vol. 25, N° 3 (03/2024)
