Titre : |
A novel transdermal EGF for skincare |
Type de document : |
texte imprimé |
Auteurs : |
Lin Zhang, Auteur ; Zhaoming Rao, Auteur ; Liebe Griebenauw, Auteur ; Yao Liu, Auteur |
Année de publication : |
2023 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Facteur de croissance épidermique transdermique Ingrédients alimentaires Peau -- Soins et hygiène Peptides Produits hydratants Transport biologique
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
Transdermal epidermal growth factor (T-EGF) is a fusion protein that can be absorbed through the skin. In T-EGF, a transdermal short peptide (TD1) and epidermal growth factor (hEGF) are fused using a Linker.
The function of TD1 is to improve the transdermal transport efficacy of the EGF. This article focuses on the evolution and advantages of T-EGF for its application in novel skin care products. |
Note de contenu : |
- Epidermal growth factor (EGF)
- Delivery of macromolecules thorough the skin barrier
- The introduction of a transdermal EGF
- Cell activity and transdermal efficiency
- The repairing and moisturizing effect
- Skin irritation evaluation
- Ex vivo eye irritation test
- Application of T-EGF in skincare formulations
- Best practices for T-EGF
- Fig. 1 : Schematic diagram of T -EGF structure
- Fig. 2 : Schematic diagram of skin structure
- Table 1 : results for in vitro skin irritation by reconstructed human epidermis (%). Test group result is significant compared to the positive control. SDS = Sodium Dodecyl Sulfate
- Table 2 : BCOP test results (mean ± SD). OD value represents mean permeability value. IVS = In Vitro Score. The UN GHS guideline are followed for the classification
- Table 3 : T-EGF basic product information and dosage recommendations |
En ligne : |
https://drive.google.com/file/d/1M-iCV0ahOM4S5GjaPY9Cjyc0UbvPhqAY/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40517 |
in GLOBAL PERSONAL CARE > Vol. 24, N° 10 (11/2023)