| Titre : |
Promoting effect of a gene expression related moisturizer on skin hydration and barrier function |
| Type de document : |
texte imprimé |
| Auteurs : |
Yi-Na Lu, Auteur ; Ya-Di Yang, Auteur ; Zhi-Yong Xie ; Jun Tian |
| Année de publication : |
2018 |
| Article en page(s) : |
p. 28-32 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Barrière cutanée
Cosmétiques
Expression génique
Peau -- Soins et hygiène
Produits hydratants
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The moisturizing performance of Gmoist® Sea-Gel was evaluated based-upon 14 healthy volunteers. It was found that skin moisture content markedly increased and TEWL effectively decreased after Gmoist® Sea-Gel applied for 7d. Then using real-time fluorescence quantitative PCR technology, HaCaT cells were cultured with Gmoist® Sea-Gel to study six genes ex¬pression level related to skin hydration and barrier function. Results showed Gmoist® Sea-Gel significantly promoted the INV, TG-1, FLG and CASP-14 mRNA's expression after 24 hour's treatment. Gmoist® Sea-Gel can upregulate cornified cell envelope related genes expression, promote the degradation of filaggrin into natural moisturizing factors to strengthen skin hydration and barrier function. |
| Note de contenu : |
- In vivo studies
- Cell viability test
- Gene expression measurement
- Gmoist Sea-Gel increased the CM and reduced the TEWL
- HaCaT cell toxicity of Gmoist Sea-Gel
- Gmoist Sea-Gel regulated the CE formation related gene expression
- Gmoist Sea-Gel promoted the FLG degradation
- Gmoist Sea-Gel slightly upregulated AQP-3 gene expression |
| En ligne : |
https://drive.google.com/file/d/1jKk5IrgdBk7as-IStqhBFFLX9mav1AMs/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30956 |
in SOFW JOURNAL > Vol. 144, N° 9 (09/2018) . - p. 28-32
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