Influencing the cutaneous carotenoid status and skin-physiological parameters by ingesting antioxidants in the form of curly-hale containing food supplements / J. Schleusener in SOFW JOURNAL, Vol. 144, N° 9 (09/2018)  

[article]  inSOFW JOURNAL > Vol. 144, N° 9 (09/2018) . - p. 2-9 Titre : Influencing the cutaneous carotenoid status and skin-physiological parameters by ingesting antioxidants in the form of curly-hale containing food supplements Type de document : texte imprimé Auteurs : J. Schleusener, Auteur ; Ceylan K. Nowbary, Auteur ; Maxim E. Darvin ; Silke Barbara Lohan ; Martina C. Meinke Année de publication : 2018 Article en page(s) : p. 2-9 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge Antioxydants Caroténoides Les caroténoïdes sont des pigments plutôt orange et jaune répandus chez de très nombreux organismes vivants. Liposolubles, ils sont en général facilement assimilables par les organismes. Ils appartiennent à la famille chimiques des terpénoïdes, formés à partir de la polymérisation d'unités isoprènes à structure aliphatique ou alicyclique. Il est généralement admis qu'ils suivent des voies métaboliques similaires à celles des lipides. Ils sont synthétisés par toutes les algues, toutes les plantes vertes et par de nombreux champignons et bactéries (dont les cyanobactéries). Collagène Compléments alimentaires Cosmétiques Elasticité Evaluation Humidité Mesure Peau -- Rides Peau -- Soins et hygiène Spectroscopie de réflectance Statistique Index. décimale : 668.5 Parfums et cosmétiques Résumé : Antioxidants are important radical scavengers protecting the body from the consequences of oxidative stress. They have to be ingested by food rich in fruits and vegetables or by food supplements. The effects of the intake of curly-kale containing food supplements on the skin are described in this paper. For this purpose, verum and placebo groups had been investigated for several months noninvasively in vivo by determining their cutaneous antioxidative status, their collagen-to-elastin index of the dermis, and various age-related skin parameters. While in the verum groups the cutaneous antioxidative status and the skin moisture increased significantly, only small changes were found in the placebo groups. The collagen content in the skin of the verum group showed a tendency towards increasing. Besides a healthy nutrition, a selected supplementation consisting of low-dosed natural carotenoids at a phyllogical concentration can improve the antioxidative capacity of the skin, thus counteracting an age-related degradation of collagen I in the dermis. Note de contenu : - METHOD : Multiple spatially resolved reflectance spectroscopy (MSRRS) - Collagen-to-elastin index of the dermis (SAAID) - Wrinkle measurement - Elasticity - Skin moisture - Study design - Statistical evaluation - RESULTS : Spatially resolved reflectance spectroscopy (MSRRS) - Collagen-to-elastin index of the dermis (SAAID) - Measurement of wrinkles - Elasticity - Skin moisture En ligne : https://drive.google.com/file/d/13kmnwiC8XwELAzVPqsddjrkuyRTQHp-Q/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30951 [article]

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Stratum corneum occlusion induces water transformation towards lower bonding state : a molecular level in vivo study by confocal Raman microspectroscopy / C. Choe in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 42, N° 5 (10/2021)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 42, N° 5 (10/2021) . - p. 482-493 Titre : Stratum corneum occlusion induces water transformation towards lower bonding state : a molecular level in vivo study by confocal Raman microspectroscopy Type de document : document électronique Auteurs : C. Choe, Auteur ; J. Schleusener, Auteur ; S. Choe, Auteur ; J. Ri, Auteur ; Jürgen Lademann, Auteur ; Maxim E. Darvin, Auteur Année de publication : 2020 Article en page(s) : p. 482-493 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Barrière cutanée Cornéocytes Dermo-cosmétologie Gonflement (physique) Huile essentielle d'amande douce Jojoba et constituants Microscopie confocale Raman Peau -- Physiologie Pénétration (physique) Vaseline Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : It is conventionally understood that occlusive effects are the retention of excessive water in the stratum corneum (SC), the increase of SC thickness (swelling) and a decrease of the transepidermal water loss. However, the influence of occlusion on water binding properties in the SC is unknown. - Methods : The action of plant-derived jojoba and almond oils, as well as mineral-derived paraffin oil and petrolatum topically applied on human skin, is investigated in vivo using confocal Raman microspectroscopy. To understand the oils' influence on the SC on the molecular level, the depth-dependent hydrogen bonding states of water in the SC and their relationship to the conformation of keratin, concentration of natural moisturizing factor (NMF) molecules and lipid organization were investigated. - Results : A significant SC swelling was observed only in petrolatum-treated skin. The water concentration was increased in oil-treated skin in the intermediate SC region (40-70% SC depth). Meanwhile, the amount of free, weakly and tightly bound water increased, and strongly bound water decreased in the uppermost SC region (0-30% SC depth). The NMF concentration of oil-treated skin was significantly lower at 50-70% SC depth. The lateral organization of lipids in oil-treated skin was lower at 0-30% SC depth. The secondary structure of keratin was changed towards an increase of β-sheet content in mineral-derived oil-treated skin and changed towards an increase of α-helix content in plant-derived oil-treated skin. - Conclusion : The occlusive properties can be summarized as the increase of free water and the transformation of water from a more strongly to a more weakly hydrogen bonding state in the uppermost SC, although some oils cause insignificant changes of the SC thickness. The accompanied changes in the keratin conformation at the intermediate swelling region of the SC also emphasize the role of keratin in the SC's water-transporting system, that is the water in the SC transports intercellularly and intracellularly in the intermediate swelling region and only intercellularly in the uppermost non-swelling region. Bearing this in mind, almond, jojoba and paraffin oils, which are not occlusive from the conventional viewpoint, have an occlusion effect similar to petrolatum on the SC. Note de contenu : - MATERIALS AND METHODS : Applied substances - Volunteers - Confocal Raman microspectroscopy - Data analysis - Statistical analysis - RESULTS : SC thickness - Depth profiles of water and NMF - Water mobility and the hydrogen bonding state of water - Secondary structure of keratin - Tertiary structure of keratin - DISCUSSION : Effect of oil occlusion on the hydrogen bonding states of water molecules - Effect of oil application on the secondary and tertiary structure of keratin - Swelling of corneocytes and water binding with NMF, lipids and keratin - Table 1 : The SC thickness (μm) of untreated skin and skin treated with four different oils in μm. The symbol '*' denotes P-values < 0.05, the symbol '**' denotes P-values < 0.01 between oil-treated and untreated skin - Table 2 : Raman features measured on the pure oils and untreated SC. The symbol '–' means absence of Raman contribution DOI : https://doi.org/10.1111/ics.12653 En ligne : https://drive.google.com/file/d/1y9mzYrs5yKXHSjToWDknu7oksvfM7fVK/view?usp=shari [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=35413 [article]

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