| Titre : |
The characterization of Pluronic P123 micelles in the presence of sunscreen agents |
| Type de document : |
texte imprimé |
| Année de publication : |
2023 |
| Article en page(s) : |
p. 470-479 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Cosmétiques
Diffusion de neutrons aux petits anglesLa diffusion de neutrons aux petits angles (DNPA) permet de sonder la matière aux échelles spatiales allant de 0.5 et 50 nm en déterminant les grandeurs moyennes qui caractérisent la taille et la forme des objets ainsi que leurs interactions. (https://www.neutron-sciences.org)
Emulsions -- Emploi en cosmétologie
Emulsions -- Stabilité
Formulation (Génie chimique)
Peau -- Soins et hygiène
Pénétration cutanée
Produits antisolaires
Surfactants
Systèmes de livraison (pharmacie)
Vectorisation
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
- Objectives : The triblock copolymer Pluronic® is widely used in the personal care industry, including sun protection, for its film-forming and solubilization capabilities. In this study, the effect of three commonly used organic UV filters (ethylhexyl methoxycinnamate [EMC], ethylhexyl triazone [EHT], and avobenzone [AVB]) on the structure of Pluronic P123 micelles was investigated.
- Methods : The Pluronic P123 micelle structure has been investigated using dynamic surface tension, nuclear magnetic resonance (NMR) and small-angle neutron scattering (SANS).
- Results : Dynamic surface tension results show strong interactions between the UV filters and Pluronic® evident by sharp changes in the surface activity of the latter. The NMR results have revealed the creation of a hydrophobic microenvironment special to the Pluronic PPO core group in the presence of UV filters. Some interaction with the hydrophilic EO was also recorded, albeit weaker. This is further confirmed by SANS, where the Pluronic P123 micelles interacted with varying strengths with the UV filters, resulting in sharp changes in their size and shape.
- Conclusions : We have demonstrated the sensitivity of the Pluronic P123 micelles to the presence of various UVA/B filters. The micelles shape varied from spherical to cylindrical as the concentration and type of the UV filters were varied. These variations in the shape are expected to have a significant effect on the sun protection factor (SPF), as it affects the solubilization of the UV filters within a formulation in addition to the formulations' rheological profile and film-forming behaviour. |
| Note de contenu : |
- MATERIALS
- METHODS : Preparation of Pluronic- UV filters solutions - Tensiometry - Nuclear magnetic resonance (NMR) - Small-angle neutron scattering (SANS)
- RESULTS AND DISCUSSION : Dynamic surface tension (DST) - Nuclear magnetic resonance (NMR) - Small-angle neutron scattering (SANS)
- Table 1 : SANS fitting parameters from P123 micelles (5 wt%) and EMC at different concentrations, in 10 wt% d6-ethanol and D2O, at 25°C - Table 2 : SANS fitting parameters from P123 micelles (5 wt%) and EHT at different concentrations, in 10 wt% d6-ethanol and D2O, at 25°C |
| DOI : |
https://doi.org/10.1111/ics.12856 |
| En ligne : |
https://drive.google.com/file/d/1wdAZR7CDALEhDuF0wkFrCPffAYeR-o2E/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=39877 |
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 45, N° 4 (08/2023) . - p. 470-479
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The characterization of Pluronic P123 micelles in the presence of sunscreen agents in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 45, N° 4 (08/2023)
