| Titre : |
Development of multifunctional Si-Ca-PEG-nAg sol–gel implant coatings from calcium-2-ethoxyethoxide |
| Type de document : |
texte imprimé |
| Année de publication : |
2021 |
| Article en page(s) : |
p. 1177–1189 |
| Note générale : |
Bibliogr. |
| Langues : |
Américain (ame) |
| Catégories : |
3-Glycidoxypropyltrimethoxysilane
Antibactériens
Argent
Calcium
Caractérisation
Chimie des surfaces
Couches minces
Implants médicaux
Matériaux hybrides
Polyéthylène glycol
Prothèses
Revêtements
Silicium
Titane
|
| Index. décimale : |
667.9 Revêtements et enduits |
| Résumé : |
Titanium implant success is compromised by microbial biofilms and aseptic loosening. This research aimed to develop robust multifunctional class II organic-inorganic hybrid coatings for implants with osteoconductive and antibacterial properties. 3-Glycidoxypropyltrimethoxysilane was coupled with organic polymer poly(ethylene) glycol-diamine (PEG-NH2) for integration into an inorganic sol backbone composed of tetraethoxysilane and calcium, which was sourced from newly synthesized calcium-2-ethoxyethoxide. Nuclear magnetic resonance and attenuated total reflectance Fourier transform infrared spectroscopy confirmed synthesis of precursors and the structure of coating constituents. Scanning electron microscopy and energy-dispersive X-ray spectroscopy (EDS) demonstrated homogenous coatings, micro-topographical surface features, and apatite-like ex vivo mineralization in simulated body fluid. Tensile adhesion testing demonstrated robust and highly adherent (15.1 ± 3.3 MPa) coatings on titanium substrates. Hybrid coatings imbedded with silver nanoparticles (nAg) significantly inhibited (P < 0.05) Staphylococcus aureus and Escherichia coli planktonic cultures and biofilm formation. These Si-Ca-PEG-nAg hybrid coatings for titanium implants offer robust multifunctional features. |
| Note de contenu : |
- MATERIALS AND METHODS : Preparation of coating materials - Characterization of coatings
- RESULTS AND DISCUSSION : Materials characterization
- Table 1 : Composition of hybrid coatings
- Table 2 Ionic composition of simulated body fluid and human blood plasma |
| DOI : |
https://doi.org/10.1007/s11998-021-00477-x |
| En ligne : |
https://link.springer.com/content/pdf/10.1007/s11998-021-00477-x.pdf |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=36223 |
in JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH > Vol. 18, N° 4 (07/2021) . - p. 1177–1189
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Development of multifunctional Si-Ca-PEG-nAg sol–gel implant coatings from calcium-2-ethoxyethoxide in JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH, Vol. 18, N° 4 (07/2021)
