[article]
Titre : |
Scalp care efficacy of a multi-herb extract |
Type de document : |
texte imprimé |
Auteurs : |
Yina Lu, Auteur ; Zhang Heng, Auteur ; Jun Tian, Auteur |
Année de publication : |
2021 |
Article en page(s) : |
p. 33-36 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Anti-inflammatoires Cosmétiques Cuir chevelu -- Soins et hygiène Extraits de plantes:Extraits (pharmacie) Malassezia Produits capillaires Statistique
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
Malassezia furfur is a lipophilic and dermatological pathogenic yeast, which normally exists on human skin, and causes tinea versicolor, seborrhoeic dermatitis, and atopic dermatitis, especially on human scalp. The multi-herb extraction, VGP, which consists of Vitex trifolia fruit, Gentiana scabra, and Polygonum multiflorum root extract was used to study its effect of anti-inflammation, controlling sebum and dandruff on scalp care. Results showed that on the model of NHEK and THP1 cell inflammation induced by Malassezia furfur, VGP can inhibit the expression of interleukin 6 (IL-6), prostaglandin E2 (PGE-2), monocyte chemoattractant protein 1 (MCP-1) and interleukin 1β (IL-1β) in a dose-dependent manner under 0.01% to 0.125% concentration. On the inflammatory model of 3D reconstructed skin induced by H2O2, VGP significantly improved the cell viability and skin structure, and reduced the production of interleukin 8 (IL-8), PGE-2, and leukotriene B4 (LTB4). During 4 week’s treatment with test shampoo containing 0.5% VGP thrice a week on 16 subjects met with different symptoms, VGP reduced the sebum content and TEWL, improved the redness, itching and dandruff on human scalp skin. Therefore, as a natural active ingredient VGP can play a role in scalp care and skin care by targeting inflammation. |
Note de contenu : |
- MATERIALS AND METHODS : VGP preparation - Maintenance of cels - Anti-inflammatory experiments on cells - Anti-inflammatory experiments on 3D reconstructed skin - Scalp care test in vivo - Statistical analysis
- RESULTS : Anti-inflammatory efficacy of VGP against M. furfur on cells - VGP inhibited the inflammation and cell damage on reconstructed skin - VGP reduced the itching and redness of human scalp skin
- Table 1 : Effect of VGP on the viability of two cells
- Table 2 : The effect of VGP on scalp redness, dandruff and itching |
En ligne : |
https://drive.google.com/file/d/1nlf8RoLehtbFeYtKSvSnZ-81El45gOIT/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=36118 |
in GLOBAL PERSONAL CARE > Vol. 22, N° 6 (06/2021) . - p. 33-36
[article]
|