Genetic integrity for a rejuvenated skin look / Marta Rull in PERSONAL CARE EUROPE, Vol. 6, N° 5 (11/2013)  

[article]  inPERSONAL CARE EUROPE > Vol. 6, N° 5 (11/2013) . - p. 61-66 Titre : Genetic integrity for a rejuvenated skin look Type de document : texte imprimé Auteurs : Marta Rull, Auteur ; Cristina Davi, Auteur ; Elena Cañadas, Auteur ; Wim Van Den Nest, Auteur ; Raquel Delgado, Auteur Année de publication : 2013 Article en page(s) : p. 61-66 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : ADN -- Réparation Antiâge:Antirides Cosmétiques Hexapeptides Peau -- Soins et hygiène Protection cutanée Index. décimale : 668.5 Parfums et cosmétiques Résumé : The daily exposure to DNA-damaging agents leads to errors that accumulate year by year as the natural repair mechanisms become less active when ageing. Among the agents that help to delete these undesired changes, FOX03a is highlighted as an essential transcriptional factor that regulates the expression of genes implied in the repair and removal of genetic errors, depending on the severity. FOX03a is then vital to maintain genetic integrity. Acetyl hexapeptide-51 amide is an innovative peptide that stimulates the same natural DNA-repair pathways as FOX03a, being able to activate the FOX03a responsive elements by 1.9 times and raise the DNA-repair pathways by 2.7 times. Besides, it protects from UV radiation and pollution, in vitro increasing cellular viability and decreasing the induced damage, and in vivo reducing UV-induced damage by 16.6%, at 2% peptide solution. Additionally, it also proved to in vitro diminish the number of senescent cells by 64.6%, which means 11 years of cellular rejuvenation. Thus, Juvefoxo peptide acts as a guardian of genetic integrity that helps to repair or remove genetic errors that can result in a skin worsening even at a macroscopic level. This hexapeptide rejuvenates and improves skin aspect, enhancing natural repairing mechanisms and raising protection from daily damaging agents. Note de contenu : - NATURAL DNA REPAIRING MECHANISMS - FOXO TRANSCRIPTIONAL FACTORS AND LONGEVITY - MATERIALS AND METHODS : Activation of FOXO3a responsive elements - DNA-repair pathways activation - Photoprotection efficacy - DNA-protective effect against photoactivated BaP - Reverting cellular senescence - In vivo repair of UV-induced DNA damage - RESULTS AND DISCUSSION : Activation of FOXO3a responsive elements - DNA-repair pathways activation - Photoprotection efficacy - DNA-protective effect against photoactivated BaP - Reverting cellular senescence - In vivo repair of UV-induced DNA damage En ligne : https://drive.google.com/file/d/1pYCJHClrtfJa4GpA_Ur9J79B_mov4ALE/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=19881 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
15686	-	Périodique	Bibliothèque principale	Documentaires	Disponible

Peptides protect normal skin and ease sensitive skin / Marta Rull in PERSONAL CARE EUROPE, Vol. 7, N° 2 (03/2014)  

[article]  inPERSONAL CARE EUROPE > Vol. 7, N° 2 (03/2014) . - p. 58-60 Titre : Peptides protect normal skin and ease sensitive skin Type de document : texte imprimé Auteurs : Marta Rull, Auteur ; Cristina Davi, Auteur ; Elena Cañadas, Auteur ; Wim Van Den Nest, Auteur ; Raquel Delgado, Auteur Année de publication : 2014 Article en page(s) : p. 58-60 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Biomolécules actives Cosmétiques Peau -- Soins et hygiène Peptides Sensibilité cutanée Index. décimale : 668.5 Parfums et cosmétiques Résumé : Every day more people realise that they present sensitive skin and its annoying symptoms and that a normal skin can easily become sensitive due to exposure to certain daily agents. Thus, enhancing the natural mechanisms of protection and directly reducing the distressing consequences of sensitive skin would certainly ameliorate skin and personal comfort. Lipotec provides four active ingredients that help to reduce sensitive skin effects and prevent them. Through different mechanisms of action, both Delisens peptide (via PAR-2 activity) and Telangyn peptide (via LL-37) specifically decrease diverse alterations induced by sensitive skin, like itching, pain, flush, redness, dilated capillaries and the potential hyperpigmentation. In order to increase normal skin protection from sensitising, Bodyfensine peptide and Thermostressine peptide reinforce the cutaneous natural defensive mechanisms along with the response towards stressing situations that may cause severe cellular damage. Therefore, this group of active molecules is not only thought to help sensitive skin sufferers to gain comfort but also decrease the risk of normal skin turning into sensitive by increasing the already present protective mechanisms of the skin. Note de contenu : - Changes in sensitive skin - Natural mechanisms for skin protection - Alleviating sensitive skin effects - Enhancing the cutaneous protective elements En ligne : https://drive.google.com/file/d/1VmbPK_LD5Bq4yfhipFiz0OdGMcsciM0q/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=20784 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
16107	-	Périodique	Bibliothèque principale	Documentaires	Disponible

Preventing cosmetic actives for skin protection / Miriam Mateu in PERSONAL CARE EUROPE, Vol. 4, N° 2 (06/2011)  

[article]  inPERSONAL CARE EUROPE > Vol. 4, N° 2 (06/2011) . - p. 47-50 Titre : Preventing cosmetic actives for skin protection Type de document : texte imprimé Auteurs : Miriam Mateu, Auteur ; Elena Cañadas, Auteur ; Nùria Almiñana, Auteur ; Raquel Delgado, Auteur ; Juan Cebriàn, Auteur ; Cristina Carreno, Auteur ; Ana Sempere, Auteur ; Wim Van Den Nest, Auteur ; Antonio Ferrer-Montiel, Auteur Année de publication : 2011 Article en page(s) : p. 47-50 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Photoprotection Produits antisolaires Protection cutanée Index. décimale : 668.5 Parfums et cosmétiques Note de contenu : - MATERIALS AND METHODS : Determination of expressed HSP70 in human keratinocytes - Determination of HSP70 induction expression after heat shok - Heat and cold protection assays - Dehydration stress assay - Photoprotection efficacy against UVB-induced stress - RESULTS AND DISCUSSION : Determination of HSP70 induction expression after heat shok - Heat and cold protection assays - Dehydration stress assay - Photoprotection efficacy against UVB-induced damage in human keratinocytes En ligne : https://drive.google.com/file/d/1Hjj0YT7vKOeD6sRr4WR9t-KuY0nX8cWI/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=13418 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
13592	-	Périodique	Bibliothèque principale	Documentaires	Disponible

Tetrapeptide to minimize facial redness and the induced negative effects of an exaggerated inflammatory response / Marta Rull in IFSCC MAGAZINE, Vol. 16, N° 1 (01-02-03/2013)

[article]  inIFSCC MAGAZINE > Vol. 16, N° 1 (01-02-03/2013) . - p. 27-34 Titre : Tetrapeptide to minimize facial redness and the induced negative effects of an exaggerated inflammatory response Type de document : texte imprimé Auteurs : Marta Rull, Auteur ; Cristina Davi, Auteur ; Elena Cañadas, Auteur ; Wim Van Den Nest, Auteur ; Raquel Delgado, Auteur Année de publication : 2013 Article en page(s) : p. 27-34 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cosmétiques Interleukines Les interleukines (IL) sont un groupe de cytokines, ainsi nommées car les premières observations semblaient montrer qu'elles étaient exprimées par les globules blancs (leucocytes, d'où -leukin) en guise de moyen de communication (d'où inter-). Les interleukines sont produites par une large variété de tissus et cellules, et que, bien que regroupées sous cette terminologie par commodité, elles ne présentent aucune parenté biochimique ni de fonction entre elles. Elles ont été classées par numéro au gré des découvertes. Au début 2006, 31 cytokines sont connues et dénommées sous l'intitulé IL. La fonction du système immunitaire dépend en grande partie des interleukines et de rares déficiences de certaines d'entre elles ont été décrites, conduisant à des maladies auto-immunes ou des immunodéficiences. Peau -- Inflammation Peau -- Soins et hygiène Peptides Index. décimale : 668.5 Parfums et cosmétiques Résumé : Inflammatory overreactions are linked to skin redness, dilated capillaries, skin flushing, hyperpigmentation and other disturbing skin manifestations that affect millions of individuals. Although its etiology is uncertain, the natural response of the immune system to damaging agents has a clearly relevant role, with kallikreins and antimicrobial compounds (like cathelicidins) being key elements. Active cathelicidins trigger a cascade of reactions that lead to a rise in pro-inflammatory cytokines and interleukins, which results in inflammation also alters skin firmness and elasticity by degrading extracellular matrix compounds. In skin with redness, the active cathelicidin LL-37 and the interleukins interleukin-6 and IL-8 present at abnormally high levels, so their diminution should consequently help to decrease the undesired visible effects. Acetyl tetrapeptide-40 not only reduced the LL-37-induced interleukin-6 and IL-8 levels, collagen degradation, melanogenesis and tyrosinase activity (linked to hyperpigmentation) i nvitro but strongly reduced facial redness, erythema and its extent in volunteers with mild rosacea after just one week. After four weeks, it provided excellent results, with visible facial improvements. Additionally, this peptide provided a noticeable photoprotective in vitro effect. Thus, this peptide is an excellent option to reduce skin redness and its associated consequences. Note de contenu : - EXPERIMENTAL : Inhibition of the release of LL-37-induced interleukins - Anti-collagenase assay - Anti-tyrosinase assay - Melanogenesis inhibition on human epidermal melanocytes - Photoprotection test on human dermal fibroblasts - Dermatological evaluation - RESULTS AND DISCUSSION : Inhibition of the release of LL-37-induced interleukins - Anti-collagenase assay - Anti-tyrosinase assay - Melanogenesis inhibition in human epidermal melanocytes - Photoprotection test in human dermal fibroblasts - Dermatological evaluation - Digital analysis of skin redness with the visia TM system Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=17829 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
14814	-	Périodique	Bibliothèque principale	Documentaires	Disponible

The contribution of neurogenic inflammation to sensitive skin : concepts, mechanisms and cosmeceutical intervention / Antonio Ferrer-Montiel in IFSCC MAGAZINE, Vol. 11, N° 4 (10-11-12/2008)

[article]  inIFSCC MAGAZINE > Vol. 11, N° 4 (10-11-12/2008) . - p. 311-315 Titre : The contribution of neurogenic inflammation to sensitive skin : concepts, mechanisms and cosmeceutical intervention Type de document : texte imprimé Auteurs : Antonio Ferrer-Montiel, Auteur ; M. Camprubi-Robles, Auteur ; Nuria Garcia-Sanz, Auteur ; Ana Sempere, Auteur ; Pierluigi Valente, Auteur ; Wim Van Den Nest, Auteur ; Cristina Carreno, Auteur Année de publication : 2009 Article en page(s) : p. 311-315 Note générale : Bibliogr. Langues : Anglais (eng) Tags : Algogens  Epidermis  Immune  system  Nociceptor  Sentitization Index. décimale : 668.5 Parfums et cosmétiques Résumé : Cutaneous neurogenic inflammation is emerging as an underlying mechanism for several skin conditions. The intimate cross-talk between the cutaneous immune system and the periperal nervous system is fundamental for skin biology. However, an imbalance or dysfunction results in the onset of an inflammatory state that is reinforced by the synergic and complementary action of both systems. Cumulative evidence indicates that the termoreceptor TRPV1 is a key player of neurogenic inflammation. This receptor is activated by both physical and chemical stimuli, and its activity is potentiated by pro-inflammatory mediators. An increase in TRPV1 activity results in an increment of neuronal excitability that leads to the release of proalgesic agents that stimulate the immune system. Therefore, the TRPV1 receptor is being considered as a cosmeceutical target, and agents that reduce its activity will be useful cosmeceuticals. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=3258 [article]

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
011000	-	Périodique	Bibliothèque principale	Documentaires	Disponible

---

1 (1 - 5 / 5)