| Titre : |
First generation of cannabis sativa stem cells : nourishing the skin microbiota |
| Type de document : |
texte imprimé |
| Auteurs : |
Oscar Expósito, Auteur ; Alejandro Guirado, Auteur ; Daniel Robustillo, Auteur ; Ana Gallego, Auteur ; Maria Mas, Auteur ; Pau Riera, Auteur ; Daniel Luna, Auteur ; Sara Laplana, Auteur ; Tarik Ruiz, Auteur ; Karsten Lingen, Auteur |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 2-7 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antiâge:Antirides
Cannabis et constituants
Cellules souches
Dermo-cosmétologie
Microbiote
Peau -- Soins et hygiène
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The skin microbiota and the brain are connected through an existing natural pathway where the microbiota is the first step. The new active Kannabia SensePLF (INCI name: Cannabis Sativa Callus Lysate), is the first generation of Cannabis sativa plant stem cells and introduces the concept of in-situ postbiotic. Through its mechanism of action, the active modulates the skin commensal microbiota to produce a positive in-situ postbiotic cocktail that ignites the synthesis of happiness related neurochemicals from the skin that connects with the brain, turning into a well-being response and a healthier and stronger skin. Several in vitro
and in vivo trials have been carried out to demonstrate the skin well-ageing effect, positive brain activation and modulation of mood state thanks to the active ingredient. |
| Note de contenu : |
- The skin : the human third brain
- The microbiota-skin brain axis
- The concept of in-situ postbiotic
- Kannabia sense : The first cannabis sativa stem celle
- In vitro efficacy : In vitro 1 : Characterization of the bacterial in-situ postbiotic - In vitro 2 : Analysis of the microbiota-skin-brain axis network
- IN VIVO EFFICACY : In vivo 1 : Evaluation of skin well-ageing effect - In vivo 2 : Evaluation of the emotional modulation
- Fig. 1 : Microbiota-skin-brain axis
- Fig. 2 : Analysis of the microbiota-skin-brain axis networks
- Fig. 3 : Oxytocin levels in NHEK
- Fig. 4 : Oxytocin levels in sensory neurons
- Fig. 5 : Clinical evaluation of wrinkles
- Fig. 6 : 3D brain model & correlation coefficient matrices
- Fig. 7 : Clinical evaluation of the brain activation fy fMRI
- Fig. 8 : Clinical evaluation of the positive emosions |
| En ligne : |
https://drive.google.com/file/d/1UUkk1xm0CMvaMTbF_oA-zBrqWQqaUHLV/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=34221 |
in SOFW JOURNAL > Vol. 146, N° 6 (06/2020) . - p. 2-7
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First generation of cannabis sativa stem cells : nourishing the skin microbiota in SOFW JOURNAL, Vol. 146, N° 6 (06/2020)
