| Titre : |
Antimicrobial testing : what do the results mean ? |
| Type de document : |
texte imprimé |
| Auteurs : |
Kevin Roden, Auteur |
| Année de publication : |
2020 |
| Article en page(s) : |
p. 27-31 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Conservateurs (chimie) -- analyse
Essais (technologie)
Tests d'efficacité
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Tests designed to determine the antimicrobial efficacy of a product, such as a preservative in a cosmetic, a sanitiser in a household cleaner, or a disinfectant, have set pass requirements.
These often specify minimum log reductions or % kill to meet the requirements of the test. This article will discuss how these tests are conducted, what these terms mean, how they are calculated and how changes in the method used for the testing may lead to variations in the results achieved.
We will also cover changes to the Laboratory Accreditation Standard, ISO 17025 with regards to Measurement of Uncertainty and Statements of Conformity and what impact these changes may have on certificates of analysis issued for Testing. |
| Note de contenu : |
- Step 1 : Preparation of the test organism
- Step 2 : Add test organisms to the sample under test
- Step 3 : Allow a desired contact period
- Step 4 : Neutralise the active
- Step 5 : Determine survivors
- Step 6 : Calculate log reduction or % kill
- Step 7 : Report the results
- What do the test reports mean ?
- What do they really mean ?
- Fig. 1 : Variation in MIC values for lab vs wild strain organisms
- Fig. 2 : Bacterial growth curve
- Fig. 3 : Organism kill rates
- Table 1 : Steps in antimicrobial testing
- Table 2 : Calculation of log reduction and % kill
- Table 3 : Comparison of log reduction and % kill
- Table 4 : Acceptance criteria
- Table 5 : Reduction criteria (log 10) for bacgeria for different test methods
- Table 6 : Log reduction required vs number of bacteria killed |
| En ligne : |
https://drive.google.com/file/d/1xzhxyzrbozDSIw9XgMZ0G4LAl_UtRvna/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=33946 |
in PERSONAL CARE EUROPE > Vol. 14, N° 2 (04/2020) . - p. 27-31
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Antimicrobial testing : what do the results mean ? in PERSONAL CARE EUROPE, Vol. 14, N° 2 (04/2020)
