Titre : |
Impact of photostability and UVA/UVA-blue light protection on free radical generation |
Type de document : |
texte imprimé |
Auteurs : |
Myriam Sohn, Auteur ; Stanislaw Krus, Auteur ; Marcel Schnyder, Auteur ; Katinka Jung, Auteur ; Marietta Seifert, Auteur |
Année de publication : |
2019 |
Article en page(s) : |
p. 2-10 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Cosmétiques -- Analyse Evaluation Formulation (Génie chimique) Lumière bleue Mesure Peau -- Soins et hygiène Produits antisolaires Protection cutanée Radicaux libres (chimie) Rayonnement ultraviolet A
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
The impact of UV-filter combination on the number of free radicals generated in sunscreen formulations and the skin following UV-VIS irradiation was assessed via electron spin resonance spectroscopy using a spin-probing approach. Four UV-filter combinations that differed in their photostability and range of UVA absorbance coverage were investigated. Fewer free radicals were generated in the sunscreen formulation when a photostable UVA filter system was used, compared to a stabilized UVA filter system. Additionally, fewer free radicals were generated in the skin when a sunscreen with long UVA protection extending to the short visible range was used, compared to a sunscreen with minimal UVA protection. This study showed that the photostability of a UV-filter system is central to the generation of free radicals in a formulation, and that long UVA-blue light protection is key for avoiding the generation of free radicals in the skin. A sunscreen product exhibiting both photostable UVA protection and long UVA-blue light protection is therefore the most appropriate choice for protecting against ROS-induced skin damage. |
Note de contenu : |
- MATERIALS AND METHODS : Sunscreen formulations - Measurement of free radicals - UV and blue light transmittance measurements with photostability assessment
- RESULTS AND DISCUSSION : Photostability profile of investigated sunscreen formulations - Absorbance profile of organic particulate UV filters
- Table 1 : Chassis of the sunscreen formulations used in both studies
- Table 2 : Composition of UV-filter combinations in % by weight
- Table 3 : Relative quantity of free radicals, N = 2
- Table 4 : Means and standard deviations for N = 3-5
- Fig. 1 : Photostability profile of the investigated sunscreens
- Fig. 2 :Free radical formation in the unstable sunscreens as a function of UV irradiation time. Data fitted with a Boltzmann sigmoidal algorithm
- Fig. 3 : Long UVA-blue light transmittance of Tinosorb M and Tinosorb A2B at 4%, 7% and 10%
- Fig. 4 : UVA-blue light transmittance of UV-filter combinations with varying quantities of particulate organic UV filters : from O% (top curve), to 5.25% (middle curve) and 13.5% of organic particulate UV filters |
En ligne : |
https://drive.google.com/file/d/1pU6mF1OhvWam8jSEoNvLW2xn5Gu1dzrM/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=32927 |
in SOFW JOURNAL > Vol. 145, N° 7/8 (07-08/2019) . - p. 2-10