Titre : |
Stable nanoemulsions - versatile applications in cosmetics and pharmacy |
Type de document : |
texte imprimé |
Auteurs : |
Gabriele Blume, Auteur ; Katinka Jung, Auteur ; Fischer Dagmar, Auteur |
Année de publication : |
2019 |
Article en page(s) : |
p. 30-33 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Cosmétiques Emulsions -- Emploi en cosmétologie Médicaments -- Administration par voie cutanée Nanoémulsions Peau -- Soins et hygiène
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
The major disadvantage in dermal drug delivery is the low penetration rate of active ingredients into the skin. To over¬corne this challenge vesicular carrier systems have gained a wide attention especially in the field of nanotechnology like e.g. liposomes, ethosomes or lipid nanoparticles.
Also nanoemulsions are considered to be promising candidates for dermal drug delivery with the advantage of low skin irritation, high drug loading capacity and drug penetration enhancement.
Among them new stable anionic nanoemulsions based on the membrane-forming emulsifier "Glyceryl Citrate/Lactate/ Linoleate/Oleate", an eatable and skin friendly emulsifier de¬rived from sunflower, became superior over other vesicular carriers. Depending on the usage of additional emollients/ oils and stabilizers two different emulsions can be obtained: a multiple water-in-oil-in-water nanoemulsion (Hydro-Tops®) or an oil-in-water nanoemulsion (Lipo-Tope). |
Note de contenu : |
- Structures of the different nano-vesicles
- Vesicle sizes and polydispersity index
- Toxicity
- Hydro-tops EGCG
- Lipo-tops tocopherol
- Fig. 1 : Structures of different nanovesicles
- Fig. 2 : Stability of encapsulated EGCG
- Fig. 3 : Autioxidative power of different EGCG formulations
- Fig. 4 : Antioxidative power of different vitamin E formulations
- Table 1 : Vesicle sizes and polydispersity |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=32729 |
in SOFW JOURNAL > Vol. 145, N° 5 (05/2019) . - p. 30-33