[article]
| Titre : |
Fullerenes improve fine wrinkles around eyes |
| Type de document : |
texte imprimé |
| Auteurs : |
Hisae Aoshima, Auteur |
| Année de publication : |
2017 |
| Article en page(s) : |
p. 37-40 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antiâge:Antirides
Antioxydants
Contour des yeux -- Soins et hygiène
Fullerènes
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Formation of fine wrinkles during the photo-ageing of skin is caused by reactive oxygen species (ROS) generated by exposure of the skin to ultraviolet (UV) light. Therefore, it is very important to quickly scavenge the ROS generated in skin. Applying a radical scavenger such as an antioxidant to skin is effective for the prevention of wrinkles. However, most antioxidants are unstable in the presence of light and heat, and easily deteriorate under exposure to UV light and heat. Hence, fullerene was hypothesised to be effective in preventing the formation of fine wrinkles .A clinical trial demonstrated that, compared to a placebo cream, a cream containing fullerene significantly reduced the area of wrinkled skin, without any adverse effects; the wrinkle-improving effect may result from the regulation of gene expression involved in wrinkle formation and skin barrier function via ROS scavenging by fullerene. |
| Note de contenu : |
- Fullerene, a radical scavenger (an antioxidant)
- Reducing fine wrinkles by the application of fullerene: Clinical trials
- Mechanism of the anti-wrinkle effect: Improving skin barrier function
- Suppression of collagenase (MMP-9) expression
- FIGURES : 1. Mechanism of wrinkle formation - 2. Synthesis/decomposition of collagen and formation of wrinkles - 3. Cosmetic ingredients containing fullerene. a) Veil fullerene, b) Moist fullerene, c) radical sponge, d) lipo fullerene - Comparison of antioxidant activities of fullerene (C60) and common antioxidants by the ?-carotene bleaching method. Ascorbyl 2-phosphate 6-palmitate (APPS) - 5. Inhibition of oxidative cytotoxicity by LipoFullerene - 6. Evaluation method of the anti-wrinkle effect. Two dimensional (2D) image analysis of replicas, with oblique illumination - 7. Variation in percentage of wrinkle (average value from 23 individuals) - 8. Recovery of skin barrier function by fullerene - 9. Expression levels of mRNA involved in wrinkle formation
- TABLE : Examination conditions of the clinical trial |
| En ligne : |
https://drive.google.com/file/d/1eCZA5wlQj4Dd2D-Fr137owW54CVifLNS/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=29312 |
in PERSONAL CARE EUROPE > Vol. 11, N° 4 (09/2017) . - p. 37-40
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Fullerenes improve fine wrinkles around eyes in PERSONAL CARE EUROPE, Vol. 11, N° 4 (09/2017)
