[article]
| Titre : |
Environmental skin protection strategies - a new clinical testing method employing a cigarette smoke pollutant model |
| Type de document : |
texte imprimé |
| Auteurs : |
Stephan Bielfeldt, Auteur ; A. Böhling, Auteur ; S. Laing, Auteur ; C. Hoppe, Auteur ; Klaus-Peter Wilhelm, Auteur |
| Année de publication : |
2016 |
| Article en page(s) : |
p. 10-16 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Dermo-cosmétologie
Etudes cliniques
Peau -- analyse
Peau -- Effets de la pollution atmosphérique
Pollution -- Effets physiologiques
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The World Health Organisation (WHO) estimates that more than 80% of people living in urban areas are exposed to air quality levels that exceed defined health limits. In addition to solar ultraviolet radiation (UVR), noxious gases, particulate matter, and ozone, which are all found in or generated by combustion smoke, are key air pollutants that have a negative impact on the skin. An indoor combustion smoke with frequent contact on humans is cigarette smoke. Smoking is associated with early skin ageing (wrinkles, skin dryness, skin discoloration, etc.), and the combination of smoking and solar UVR has been reported to further exacerbate skin ageing processes. Using cigarette smoke as a pollutant model, this paper describes a new validated clinical method to evaluate the "protective" effects of specific cosmetic products against gaseous pollution exposure. The skin of human volunteers is treated with the product under test, exposed to cigarette smoke and then peroxidation of human sebum or skin barrier lipids is assessed using LC-MS. Key advantages of this method are the small number of volunteers required, and the reproducibility and sensitivity of the method to detect protective and antioxidative properties of cosmetic active ingredients and cosmetic formulations. Pollutant cigarette smoke is a suitable substance containing all key pollution components that can be used in human volunteers without ethical issues as compared to other pollution sources. Furthermore, this method enables us to induce, under standardised clinical laboratory conditions, pollution stress on "living skin" in healthy subjects. |
| En ligne : |
https://drive.google.com/file/d/1kD7Up7r5CcQu7PfpUTKTLxg1ooeVqD-D/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=27853 |
in SOFW JOURNAL > Vol. 142, N° 11 (11/2016) . - p. 10-16
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Environmental skin protection strategies - a new clinical testing method employing a cigarette smoke pollutant model in SOFW JOURNAL, Vol. 142, N° 11 (11/2016)
