[article]
| Titre : |
High levels of free radicals in suncare products induce acne aestivalis in sensitive subjects |
| Type de document : |
texte imprimé |
| Auteurs : |
Katinka Jung, Auteur ; Thomas Herrling, Auteur ; Ulrike Heinrich, Auteur ; Hagen Tronnier, Auteur ; Marcel Schnyder, Auteur ; Bernd Herzog, Auteur |
| Année de publication : |
2016 |
| Article en page(s) : |
p. 2-8 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Acné L'acné (nom féminin) est une dermatose (maladie de la peau) inflammatoire des follicules pilosébacés (glandes sécrétant le sébum, à la racine des poils) avec formation de comédons.
Cette maladie de la peau est représentée dans sa forme la plus fréquente par l'acné polymorphe juvénile qui touche les adolescents, mais qui ne résume pas toutes les acnés. Il existe aussi des acnés exogènes d'origine professionnelle, médicamenteuse, cosmétique...
Cosmétiques -- Toxicologie
Peau -- Inflammation
Produits antisolaires
Radicaux libres (chimie)
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The market segment of suncare products for protection of sensitive skin against photodermatosis is growing. Speciflcally, proection against Acne aestivalis ("Mallorca-Acne") is perceived as a strong claim for this product category. There is evidence that peroxide free radicals, deriving from certain formulation components, are involved in the induction of photo-toxic skin reactions. These UV-incluced free radicals can be assessed by an ESR-based method called Radical Potential (RP), by exposing formulations to UV radiation. The aim of this study was to find a correlation between the amount of UV inducible peroxides of sunscreen products and the clinical symptoms of Acne aestivalis. Two sunscreen formulas (SPF 30) containing organic UV-filters only, with an identical protection in the UV B region and a comparable protection in the UV A spectral range, have been produced. For both formulations the amount of UV-inducible free radicals was assessed by the RP (Radical Potential). In addition, bath formulas were tested in a clinical study with subjects with a history of Acne aestivalis. Very different RP values (levels of UV-induced free radicals) and completely different skin reactivity have been obtained, where an excellent correlation between the in vitro-parameter (RP) and the clinical symptoms could be shown. To our knowledge these results for the first time provide direct evidence for a strong correlation between UV inducible free radicals of formulations and the potential to induce A. aestivalis in sensitive subjects. Furthermore it offers a nationale for the development of law risk sunscreen formulations by selection of suitable filter systems combined with in situ ESR analysis. |
| En ligne : |
https://drive.google.com/file/d/1xcreNyUK6raAM1sApbAVUsl5N9UabkIH/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26668 |
in SOFW JOURNAL > Vol. 142, N° 3 (03/2016) . - p. 2-8
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High levels of free radicals in suncare products induce acne aestivalis in sensitive subjects in SOFW JOURNAL, Vol. 142, N° 3 (03/2016)
