[article]
Titre : |
Derivatization procedure and HPLC determination of 2-ethoxyethanol in cosmetic samples |
Type de document : |
texte imprimé |
Auteurs : |
Emilia Mariani, Auteur ; C. Villa, Auteur ; C. Neuhoff, Auteur ; Stefano Dorato, Auteur |
Année de publication : |
1999 |
Article en page(s) : |
p. 199–205 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Tags : |
'2-méthoxyéthanol' 'Produits de beauté' Cosmétiques Dérivatisation HPLC |
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
Ethylene glycol monoethyl ether or 2-ethoxyethanol finds a wide industrial application as a solvent for lacquers, inks, dyes, household products and as a surfactant. It is also found in cosmetics such as nail products, face cleansers, liquid soaps, oral care products, hair colours and fixatives. The potential hazard to human health of 2-ethoxyethanol following inhalation and dermal exposure has been recently reviewed and the European Cosmetic, Toiletry and Perfumery Association (COLIPA) has issued recommendations suggesting its non-use as a cosmetic ingredient. Therefore a simple and fast monitoring method is necessary for routine control to identify and quantify 2-ethoxyethanol in raw materials and finished cosmetics. We have developed a sensitive and selective method to determine 2-ethoxyethanol in complex matrices by precolumn derivatization with 1-naphthyl isocyanate and RP-HPLC analysis. Four laboratory-made cosmetic formulations (a nail lacquer remover, a baby oil, a skin lotion and an emollient O/W emulsion) containing three known amounts of 2-ethoxyethanol (0.1%, 2.0%, 5.0%) have been studied. The obtained results show that this chromatographic procedure provides a good estimate of the true concentration of 2-ethoxyethanol in complex matrices and it is reliable for routine analyses in quality control. |
DOI : |
10.1046/j.1467-2494.1999.203164.x |
En ligne : |
https://onlinelibrary.wiley.com/doi/10.1046/j.1467-2494.1999.203164.x |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=26491 |
in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 21, N° 3 (06/1999) . - p. 199–205
[article]
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