Titre : |
Skin pigmentation controlled via intelligent targeting |
Type de document : |
texte imprimé |
Auteurs : |
Joan Gonzà lez, Auteur ; Marisabel Mourelle, Auteur |
Année de publication : |
2015 |
Article en page(s) : |
p. 21-24 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Agents de blanchiment Cosmétiques Encapsulation Peau -- Soins et hygiène Peptides
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
X50 Pure White is a novel and potent lightening agent designed in an intelligent targeting delivery (ITD) to melanocytes. The active ingredient is encapsulated in a system that enables sustainable release and enhances the effect of the active ingredient. Whitening effect results come from the synergy of blocking aMSH mediated reactions in melanocytes and the effect of encapsulated peptide that inhibits the formation of melanin under stimulated conditions. Therefore, X50 Pure White acts on pigmented areas and prevents the formation of new spots at a concentration as low as 0.001% which proves the effectiveness of the technology as well as providing an excellent safety profile. |
Note de contenu : |
- CAPSULES TARGETING MELANOCYTES
- RESULTS AND DISCUSSION : Affinity of ligand peptide to MC1 receptors in melanocyte - Effect of the encapsulated peptide on tyrosinase activity under basal conditions - Efficacy of the encapsulated peptide on melanin content stimulated by aMSH - Efficacy of encapsulated peptide : effect on melanin content in 3D skin model ( pigmented and reconstituted skin ) - Cell selectivity and intracellular fate
- CLINICAL EFFICACY : Clinical assessment of whitening effect in Asian volunteers, chromametry evaluation, and comparative study controlled by placebo |
En ligne : |
https://drive.google.com/file/d/1r04IzqsR941sNpGyf8Gl36vzNjy_NuWC/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=23450 |
in PERSONAL CARE EUROPE > Vol. 8, N° 2 (03/2015) . - p. 21-24