| Titre : |
Lenitive and antiphotoageing properties of C. asiatica |
| Type de document : |
texte imprimé |
| Auteurs : |
Giada Maramaldi, Auteur |
| Année de publication : |
2014 |
| Article en page(s) : |
p. 37-41 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antiâge
Antioxydants
Cosmétiques
Extraits de plantes:Extraits (pharmacie)
Produits antisolaires
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
The investigated C. asiatica-purified extract (CentevitaTM) has shown anti-ageing topical efficacy acting on free radical-induced oxidative stress, cytokine-induced skin inflammaging, whereas no statistical significance was achieved in the SCB count.
As per the MDA assay, although the observed reduction of the formation of MDA was quite remarkable, it has shown no statistical significance due to the damage which occurred to one of the control samples. It would be necessary to repeat the MDA assay, if possible with a higher sample numerosity, in order to correctly define the free radical scavenging properties of the extract.
On the other side, the extract has shown a clear prevention of the phenomenon of glycation, targeting a pleiotropic and complementary way the biochemical and cellular bases of skin ageing. Although several publications confirm the biological activity of C. asiatica compounds,1517 the underlying mechanisms involved in the skin physiological effects are yet not fully understood even if gene expression changes have been reported in human fibroblasts.
The clinical evaluations have further confirmed the observed in vitro properties. Additional investigations are needed to further confirm the observed results as well as elucidate the molecular mechanisms at the base of the biological activity. |
| Note de contenu : |
- Human skin explants
- Photoageing, anti-inflammatory and DNA protective activity
- Anti-glycation activity
- Clinical trial on healthy volunteers |
| En ligne : |
https://drive.google.com/file/d/1O5ceFF5SVQjjQ_tXN9CydfBX4Bsg-i4q/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=21592 |
in PERSONAL CARE EUROPE > Vol. 7, N° 4 (06/2014) . - p. 37-41
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Lenitive and antiphotoageing properties of C. asiatica in PERSONAL CARE EUROPE, Vol. 7, N° 4 (06/2014)
