| Résumé : |
Pressure sensitive adhesives have numerous health care applications; one innovative use is in transdermal drug delivery system, such as nitroglycerin patches that patients use to treat angina or nicotine patches for smoking cessation.
Transdermal drug delivery systems offer many advantages over conventional oral medications, largely because they deliver less medication to achieve the same therapeutic effect. Oral medications are absorbed in the gastrointestinal system, metabolized by the liver, and ultimately circulated by the bloodstream through the body. With any drug delivery system, the level of medication in the blood fluctuates, hitting both peaks and troughs. Using oral delivery, these peaks and troughs can be extreme, especially with frequent dosage regimens. A variety of side effects, including gastrointestinal effects, can occur when using oral medications, especially as peak blood levels are achieved. |
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Accueil
Developing a drug-in-adhesive design for transdermal drug delivery in ADHESIVES AGE, Vol. 38, N° 10 (09/1995)
