[article]
| Titre : |
A new nonionic ascorbic acid derivative |
| Type de document : |
texte imprimé |
| Auteurs : |
Takeshi Nagata, Auteur ; Yoshiki Yamaguchi, Auteur ; Toshiya Tsujino, Auteur ; Shinobu Ito, Auteur ; Takahiro Fujimoto, Auteur ; Masato Yoshioka, Auteur |
| Année de publication : |
2014 |
| Article en page(s) : |
p. 36-38 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Antiâge
Antibactériens
Biomolécules actives
Composés amphiphiles
Cosmétiques
Fibroblastes
Ingrédients cosmétiques
Peau -- Soins et hygiène
Tests de toxicité
Vitamine C
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
In cosmetic products, ascorbic acid derivatives are widely used, because of the instability of ascorbic acid (AsA) (called vitamin C as its alias). As a new nonionic and amphiphilic ascorbic-acid derivative, 2-glyceryl-3-octyl ascorbate (GO-VC), which is synthesised by introducing an octyl and a glyceryl group into ascorbic acid structure, has been recently developed. Due to its unique chemical structure, in addition to the effects of AsA, GO-VC is expected to have a humectant effect derived from glycerin and an anti-bacterial property derived from octanol, and also is highly likely to have a fibroblast activation ability, and a melanogenesis-suppressing and skin pore and wrinkle improving effect. GO-VS's safety tests, which include a human skin-sensitivity test [repeat insult patch test (RIPT)], ocular irritation test [bovine corneal opacity and permeability (BCOP) assay], genetic toxicity (Ames test), and clinical human skin patch test, have been performed, confirming the safety of GO-VC. |
| Note de contenu : |
- FUNCTIONS OF GO-VC : The fibroblast proliferating ability of GO-VC - The melanogenesis-suppressing ability of GO-VC - The result of closed patch test of GO-VC - The beautifying effect of GO-VC |
| En ligne : |
https://drive.google.com/file/d/1TRdaSTdHfD1FQGirbml92r5-a_XYG6BA/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=20469 |
in PERSONAL CARE EUROPE > Vol. 7, N° 1 (02/2014) . - p. 36-38
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A new nonionic ascorbic acid derivative in PERSONAL CARE EUROPE, Vol. 7, N° 1 (02/2014)
