| Titre : |
Hair follicle protection from oxidative damage |
| Type de document : |
texte imprimé |
| Auteurs : |
C. Gondran, Auteur ; C. Meyrignac, Auteur ; A. Perrin, Auteur ; S. Ratz, Auteur ; Jean-Marie Botto, Auteur ; Nouha Domloge, Auteur ; P. Mouser, Auteur |
| Année de publication : |
2012 |
| Article en page(s) : |
p. 89-92 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Cheveux -- Soins et hygiène
Stress -- Effets physiologiques
Stress oxydatif
|
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
Oxidative stress is a leading cellular ageing mechanism generated by a multitude of endogenous reactions and environmental factors. Even if the hair follicle (HF) is not directly exposed to environmental stress at the same level as the superficial layer of the skin, it can nevertheless exhibit signs of alteration that affect its function. An increased number of studies established the contribution of oxidative stress in hair loss and greying processes.
Taking into consideration the importance of antioxidative prevention in the field of hair biology, we developed a biofunctional pea extract and tested its efficacy on human scalp skin explants containing HF. The outcomes on HF morphology, as well as the expression of the antioxidant enzyme catalase, were investigated after stress exposure.
Our results obtained in an ex vivo model showed that HFs pretreated with the extract exhibited fewer signs of damage. This effect could be related to an increase in catalase expression in treated scalp biopsies. Moreover, the protective effect of the extract was also revealed by the reduction of stress-induced markers ant the maintenance of the HF regeneration capacity marker.
This study emphasises the importance of HF protection against oxidative stress, which can have damaging effects on hair structure, hair growth, and hair colour. |
| Note de contenu : |
- MATERIALS AND METHODS : Treatment of scalp biopsies and isolated hair follicles - Histological and immuno-histological analyses
- RESULTS : Catalase expression - Limiting hair follicle damage - Preventing stress-induced decrease in melanin content |
| En ligne : |
https://drive.google.com/file/d/1rW0PF1K3SEQPgL0o2tiMG0xtmqEnng7t/view?usp=drive [...] |
| Format de la ressource électronique : |
Pdf |
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=13402 |
in PERSONAL CARE EUROPE > Vol. 5, N° 1 (02/2012) . - p. 89-92
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