Hair follicle protection from oxidative damage / C. Gondran in PERSONAL CARE EUROPE, Vol. 5, N° 1 (02/2012)  

[article]  inPERSONAL CARE EUROPE > Vol. 5, N° 1 (02/2012) . - p. 89-92 Titre : Hair follicle protection from oxidative damage Type de document : texte imprimé Auteurs : C. Gondran, Auteur ; C. Meyrignac, Auteur ; A. Perrin, Auteur ; S. Ratz, Auteur ; Jean-Marie Botto, Auteur ; Nouha Domloge, Auteur ; P. Mouser, Auteur Année de publication : 2012 Article en page(s) : p. 89-92 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cheveux -- Soins et hygiène Stress -- Effets physiologiques Stress oxydatif Index. décimale : 668.5 Parfums et cosmétiques Résumé : Oxidative stress is a leading cellular ageing mechanism generated by a multitude of endogenous reactions and environmental factors. Even if the hair follicle (HF) is not directly exposed to environmental stress at the same level as the superficial layer of the skin, it can nevertheless exhibit signs of alteration that affect its function. An increased number of studies established the contribution of oxidative stress in hair loss and greying processes. Taking into consideration the importance of antioxidative prevention in the field of hair biology, we developed a biofunctional pea extract and tested its efficacy on human scalp skin explants containing HF. The outcomes on HF morphology, as well as the expression of the antioxidant enzyme catalase, were investigated after stress exposure. Our results obtained in an ex vivo model showed that HFs pretreated with the extract exhibited fewer signs of damage. This effect could be related to an increase in catalase expression in treated scalp biopsies. Moreover, the protective effect of the extract was also revealed by the reduction of stress-induced markers ant the maintenance of the HF regeneration capacity marker. This study emphasises the importance of HF protection against oxidative stress, which can have damaging effects on hair structure, hair growth, and hair colour. Note de contenu : - MATERIALS AND METHODS : Treatment of scalp biopsies and isolated hair follicles - Histological and immuno-histological analyses - RESULTS : Catalase expression - Limiting hair follicle damage - Preventing stress-induced decrease in melanin content En ligne : https://drive.google.com/file/d/1rW0PF1K3SEQPgL0o2tiMG0xtmqEnng7t/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=13402 [article]

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A vitaminizing boost to improve scalp health / A. Perrin in SOFW JOURNAL, Vol. 149, N° 3 (03/2023)  

[article]  inSOFW JOURNAL > Vol. 149, N° 3 (03/2023) . - p. 12-19 Titre : A vitaminizing boost to improve scalp health Type de document : texte imprimé Auteurs : A. Perrin, Auteur ; A. Le Mestr, Auteur ; I. Garcia, Auteur ; C. Meyrignac, Auteur ; Christophe Capallere, Auteur ; X. Qu, Auteur ; Y. Jiang, Auteur ; Jean-Marie Botto, Auteur ; Anne-Françoise Clay, Auteur ; Isabelle Imbert, Auteur Année de publication : 2023 Article en page(s) : p. 12-19 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antipelliculaires Cuir chevelu -- Soins et hygiène Dermo-cosmétologie Extraits de plantes:Extraits (pharmacie) Malassezia Sclaréolide Le sclaréolide est un produit naturel de lactone sesquiterpénique dérivé de diverses sources végétales, notamment la Salvia sclarea, la Salvia yosgadensis, et le tabac à cigare. C'est un analogue proche du sclaréol, un composé antifongique végétal. Il est utilisé comme parfum dans les cosmétiques et a été commercialisé plus récemment comme supplément de perte de poids, bien qu'il n'y ait aucune preuve clinique à l'appui de cet effet. Vitamine D Index. décimale : 668.5 Parfums et cosmétiques Résumé : A new botanical extract was developed by Ashland to reduce dandruff formation. It is a natural and biodegradable product which contains sclareolide purified from clary sage flowers, a plant ancestrally used for its purifying and healing properties. A study performed by artificial intelligence pointed out a predictive link between the sclareolide molecule and the vitamin D3, known to play an important role in skin physiology as epidermal differentiation or microbial defenses. Based on these data, this botanical extract was investigated on scalp health improvement in order to decrease dandruff, a widespread uncomfortable scalp skin condition. In a first part, the efficacy of the clary sage extract was studied on yeast cultures, on structural markers of the epidermis and on vitamin D activation. In a second part, a clinical study was conducted on subjects affecting by dandruff and treated for 4 weeks with a leave on scalp formulation containing the botanical extract or a placebo. This study demonstrated the benefit of this new product on scalp health by reinforcing the skin barrier function and limiting the appearance of dandruff in association with activation of vitamin D3. Note de contenu : - MATERIALS AND METHODS : Culture of Malassezia restricta - MIC determination - Scalp skin culture - sRHE culture - Fluorescent stainings - Lucifer yellow staining - Image acquisition and statistical analyses - Dosage cytokine - Clinical evaluation - RESULTS : Inhibitory effect on yeast growth - Vitamin D activation - Scalp barrier protection - Dandruff improvement En ligne : https://drive.google.com/file/d/1vE-SSx8EBzK4uGn7qkmAjVla1XLjsCUL/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=38937 [article]

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