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SOFW JOURNAL . Vol. 144, N° 9Anti-ageing - Baby care - Skin careMention de date : 09/2018 Paru le : 12/09/2018 |
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Ajouter le résultat dans votre panierInfluencing the cutaneous carotenoid status and skin-physiological parameters by ingesting antioxidants in the form of curly-hale containing food supplements / J. Schleusener in SOFW JOURNAL, Vol. 144, N° 9 (09/2018)
[article]
Titre : Influencing the cutaneous carotenoid status and skin-physiological parameters by ingesting antioxidants in the form of curly-hale containing food supplements Type de document : texte imprimé Auteurs : J. Schleusener, Auteur ; Ceylan K. Nowbary, Auteur ; Maxim E. Darvin ; Silke Barbara Lohan ; Martina C. Meinke Année de publication : 2018 Article en page(s) : p. 2-9 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge
Antioxydants
CaroténoidesLes caroténoïdes sont des pigments plutôt orange et jaune répandus chez de très nombreux organismes vivants. Liposolubles, ils sont en général facilement assimilables par les organismes. Ils appartiennent à la famille chimiques des terpénoïdes, formés à partir de la polymérisation d'unités isoprènes à structure aliphatique ou alicyclique. Il est généralement admis qu'ils suivent des voies métaboliques similaires à celles des lipides. Ils sont synthétisés par toutes les algues, toutes les plantes vertes et par de nombreux champignons et bactéries (dont les cyanobactéries).
Collagène
Compléments alimentaires
Cosmétiques
Elasticité
Evaluation
Humidité
Mesure
Peau -- Rides
Peau -- Soins et hygiène
Spectroscopie de réflectance
StatistiqueIndex. décimale : 668.5 Parfums et cosmétiques Résumé : Antioxidants are important radical scavengers protecting the body from the consequences of oxidative stress. They have to
be ingested by food rich in fruits and vegetables or by food supplements. The effects of the intake of curly-kale containing food supplements on the skin are described in this paper. For this purpose, verum and placebo groups had been investigated for several months noninvasively in vivo by determining their cutaneous antioxidative status, their collagen-to-elastin index of the dermis, and various age-related skin parameters. While in the verum groups the cutaneous antioxidative status and the skin moisture increased significantly, only small changes were found in the placebo groups. The collagen content in the skin of the verum group showed a tendency towards increasing.
Besides a healthy nutrition, a selected supplementation consisting of low-dosed natural carotenoids at a phyllogical concentration can improve the antioxidative capacity of the skin, thus counteracting an age-related degradation of collagen I in the dermis.Note de contenu : - METHOD : Multiple spatially resolved reflectance spectroscopy (MSRRS) - Collagen-to-elastin index of the dermis (SAAID) - Wrinkle measurement - Elasticity - Skin moisture - Study design - Statistical evaluation
- RESULTS : Spatially resolved reflectance spectroscopy (MSRRS) - Collagen-to-elastin index of the dermis (SAAID) - Measurement of wrinkles - Elasticity - Skin moistureEn ligne : https://drive.google.com/file/d/13kmnwiC8XwELAzVPqsddjrkuyRTQHp-Q/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30951
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Code-barres Cote Support Localisation Section Disponibilité 20161 - Périodique Bibliothèque principale Documentaires Disponible Harnessing discoveries in epigenetics to help revitalize fibroblasts / Sabine Pain in SOFW JOURNAL, Vol. 144, N° 9 (09/2018)
[article]
Titre : Harnessing discoveries in epigenetics to help revitalize fibroblasts : BASF's new anti-aging actives target epigenetic mechanisms Type de document : texte imprimé Auteurs : Sabine Pain, Auteur ; Florence Trombini, Auteur ; Valérie André-Frei ; Corinne Reymermier Année de publication : 2018 Article en page(s) : p. 10-15 Langues : Anglais (eng) Catégories : Antiâge
Biomolécules actives
Cosmétiques
Densité cutanée
EpigénétiqueL'épigénétique (mot-valise de "épigenèse" et "génétique") est la discipline de la biologie qui étudie la nature des mécanismes modifiant de manière réversible, transmissible (lors des divisions cellulaires) et adaptative l'expression des gènes sans en changer la séquence nucléotidique (ADN)
"Alors que la génétique correspond à l'étude des gènes, l'épigénétique s’intéresse à une "couche" d’informations complémentaires qui définit comment ces gènes vont être utilisés par une cellule ou… ne pas l'être".
"C'est un concept qui dément en partie la "fatalité" des gènes".
Extraits de plantes:Extraits (pharmacie)
Fibroblastes
Peau -- Soins et hygiène
Protéines
Régénération (biologie)Index. décimale : 668.5 Parfums et cosmétiques Résumé : To explore the field of epigenetics in greater detail, BASF researchers have joined forces and established an interdisciplinary innovation platform. Together with experts from public and private research institutions, they are exploring how modulations to our gene expression, caused by either chronological aging or environmental factors, can be mapped and controlled. New anti-aging active ingredients harness the platform's findings. Dermagenist®, an extract of Origanum majorana leaves, is the first active ingredient that re-activates fibroblasts by protecting them from epigenetic modifications and stimulating their vitality through LOXL1 promoter re-activation. A clinical study demonstrated an 18 % improvement in skin density after tvvo months of application, and a 15% improvement in skin firmness after three months. RNAge®, an extract of Hippophae rhamnoides seeds, fights chronological microRNA Let-7b dysregulation. Researchers has demonstrated that Let-7b is involved in epigenetic regulation and the balancing of proteins in both the extracellular matrix and the proteoglycan network required for a well-balanced dermal structure. RNAge inhibited Let-7b expression by 39 % versus the untreated control. The skin rebuilds from deep within, recovering its density (+26%) and firmness (+18.5%) for a healthy and youthful appearance. Note de contenu : - REAWAKENING FIBROBLASTS' POTENTIAL
- PROOF OF CONCEPT : IN VITRO ASSESSMENTS : Effect of dermagenist on LOXL1 mRNA expression - Effect of dermagenist on pro-collagen 1 and BMP-1 - Effect of dermagenist on actin organization
- PROOF OF CONCEPT : IN VIVO ASSESSMENTS : Effect of dermagenist on dermal density and skin firmness - Helping fibroblasts renew vital proteins - Epigenetic protein equalizer miRNA let-7b
- PROOF OF CONCEPT : IN VITRO ASSESSMENTS : Effect of RNAge on miRNA let-7b expression - Effect of RNAge on structural properties of the dermis
- PROOF OF CONCEPT : IN VIVO ASSESSMENTS : Effect of RNAge on dermal density, skin firmness and half-chin angle
Table : Five proteins modulated by miRNA let-7bEn ligne : https://drive.google.com/file/d/1r3HsNZWeeQ_owSp3f4-gKWUyaxQs2YZk/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30952
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Code-barres Cote Support Localisation Section Disponibilité 20161 - Périodique Bibliothèque principale Documentaires Disponible New data on topical peptide for needle-free facial remodeling / Mathias Gempeler in SOFW JOURNAL, Vol. 144, N° 9 (09/2018)
[article]
Titre : New data on topical peptide for needle-free facial remodeling Type de document : texte imprimé Auteurs : Mathias Gempeler, Auteur ; Sonia Dawson, Auteur ; Remo Campiche Année de publication : 2018 Article en page(s) : p. 16-20 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge
Composés organiques -- Synthèse
Cosmétiques
Hyaluronique, acideL'acide hyaluronique est un type de polysaccharide (plus précisément une glycosaminoglycane) non fixé à une protéine centrale et largement réparti parmi les tissus conjonctifs, épithéliaux et nerveux animaux.
Il se trouve notamment dans l'humeur vitrée et le liquide synovial. Il est l'un des principaux composants de la matrice extracellulaire ainsi que de certaines mucoprotéines lorsqu'il est associé à une fraction protéique.
Depuis les années 1990, il est très utilisé dans divers dispositifs médicaux, médicamenteux et cosmétiques (présenté dans ce dernier cas comme "antistatique, humectant, hydratant, conditionneur cutané, anti-âge, etc."), bénéficiant d'un effet de mode grandement soutenu par une large publicité commerciale.
Contribuant de façon significative à la prolifération et à la migration des cellules, l'acide hyaluronique est aussi impliqué dans la progression de certains cancers. (Wikipedia)
Peau -- Soins et hygiène
PeptidesIndex. décimale : 668.5 Parfums et cosmétiques Résumé : Hyaluronic acid (HA) or hyaluronan is a compound found in skin which is crucial to the smooth and full appearance of the face. It is frequently used as a filler injection in the cosmetic surgery industry. Since 2006, DSM Nutritional Products Ltd. (DSM) has known that its proprietary peptide molecule SYN®HYCAN (INCI: Tetradecyl aminobutyroylvalylaminobutyric Urea Trifluoroacetate) was effective in significantly upregulating hyaluronic acid expression within the skin itself. The aim of the research presented here was to make its demonstrated efficacy tangible and visible with novel technologies.
The data shows just how much this peptide boosts HA synthesis in dermal and epidermal cells in vitro and ex vivo. Moreover, thanks to cutting-edge 3D visualization technology and a novel, non-contact compression device, we can see how this compound significantly improves skin volume and restores firmness across multiple facial areas in vivo. Human ileedback has also delivered useful results. Over 87 % of panelists reported that their skin felt supple and smooth and nearly 70 % confirmed that their skin had more elasticity.
DSM's peptide solution can therefore be used as an effective cosmetic alternative to dermal fillers or to enhance the effects of HA injections in between treatments.Note de contenu : - The rise and rise of hyaluronic acid
- Boosting HA with peptides
- In vitro studies
- New ex vivo study
- New in vivo studies
- An injection-free way to firmer facial skin
- Fig. 1 : Different facial zones that can be augmented by dermal fillers
- Fig. 2 : Mimicking TGFβ1 activation for increased HA synthesis
- Fig. 3 : HA synthesis in keratinocyte (Test A) and fibroblast (Test B) cell culture
- Fig. 4 : Tect C - increase in biosynthesis (%) after treatment with DSM's peptide, regular TGFβ1, and a control
- Fig. 5 : Visible increase in hyaluronic acid ex vivo (blue staining). UVR = UV radiation
- Fig. 6 : Semi-quantitative analysis using image J software. *p<0.05 vs vehicle by paired student's t-test
- Fig. 7a 3D imaging showing skin volume change over time (base formulation without SYN-HYCAN)
- Fig. 7b 3D imaging showing skin volume change over time (base formulation with 2.5% SYN-HYCAN
- Fig. 8 : Skin firmness at day 0 and day 29 after treatment with DSM's peptide at 2.5%, the base formulation only, and a 3% competitor formulation. Shown is the depth of the skin's deformation evoked by the DynaSKIN device. After 29 days of treatment with a 2.5% SYN-HYCAN formulation we found a significantly smaller deofmration indicative for firmer skinEn ligne : https://drive.google.com/file/d/1gTdDjl3_8-5czFfOxns4gEm0ye_siVYB/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30954
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Code-barres Cote Support Localisation Section Disponibilité 20161 - Périodique Bibliothèque principale Documentaires Disponible Deep arctic marine extract for deep extracellular matrix engineering and digital anti-aging efficacy / Andrea Esplugas in SOFW JOURNAL, Vol. 144, N° 9 (09/2018)
[article]
Titre : Deep arctic marine extract for deep extracellular matrix engineering and digital anti-aging efficacy Type de document : texte imprimé Auteurs : Andrea Esplugas, Auteur ; Elaine Ferreira, Auteur ; Julia A. Boras ; Silvia Pastor Année de publication : 2018 Article en page(s) : p. 22-27 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge
Antiâge:Antirides
Contour des yeux -- Soins et hygiène
Cosmétiques
Elasticité
Evaluation
Extraits de plantes:Extraits (pharmacie)
Peau -- Soins et hygiène
Régénération (biologie)Index. décimale : 668.5 Parfums et cosmétiques Résumé : Little of the ocean and its intertwined ecosystems have been explored, although it is the most untapped potential source for the discovery of novel cosmetic active ingredients. From an Arctic scientific expedition, a novel active ingredient was discovered (ArctalisTM : Pseudoalteromonas Ferment Extract) aimed at restructuring ECM key components with an excellent wrinkle smoothing and firming effect. Arctalis restores skin hydration and natural glow while also protecting skin from digital pollution or blue light. Note de contenu : - MATERIALS AND METHODS : Epidermal regeneration - Dermo-epidermal cohesion - Viscoelasticity enhancement - Rejuvenation capacity - Digital anti-aging - Double blind assessment of eye care efficacy
- RESULTS AND DISCUSSION : Epidermal regeneration - Epidermal and dermal restructuring - Viscoelasticity enhancement - Rejuvenation capacity - Digital anti-aging - Double blind assessment of eye care efficacyEn ligne : https://drive.google.com/file/d/1-Ve-d5eJR5VI24OQoHWB14FFx67Lry3z/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30955
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Code-barres Cote Support Localisation Section Disponibilité 20161 - Périodique Bibliothèque principale Documentaires Disponible Promoting effect of a gene expression related moisturizer on skin hydration and barrier function / Yi-Na Lu in SOFW JOURNAL, Vol. 144, N° 9 (09/2018)
[article]
Titre : Promoting effect of a gene expression related moisturizer on skin hydration and barrier function Type de document : texte imprimé Auteurs : Yi-Na Lu, Auteur ; Ya-Di Yang, Auteur ; Zhi-Yong Xie ; Jun Tian Année de publication : 2018 Article en page(s) : p. 28-32 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Barrière cutanée
Cosmétiques
Expression génique
Peau -- Soins et hygiène
Produits hydratantsIndex. décimale : 668.5 Parfums et cosmétiques Résumé : The moisturizing performance of Gmoist® Sea-Gel was evaluated based-upon 14 healthy volunteers. It was found that skin moisture content markedly increased and TEWL effectively decreased after Gmoist® Sea-Gel applied for 7d. Then using real-time fluorescence quantitative PCR technology, HaCaT cells were cultured with Gmoist® Sea-Gel to study six genes ex¬pression level related to skin hydration and barrier function. Results showed Gmoist® Sea-Gel significantly promoted the INV, TG-1, FLG and CASP-14 mRNA's expression after 24 hour's treatment. Gmoist® Sea-Gel can upregulate cornified cell envelope related genes expression, promote the degradation of filaggrin into natural moisturizing factors to strengthen skin hydration and barrier function. Note de contenu : - In vivo studies
- Cell viability test
- Gene expression measurement
- Gmoist Sea-Gel increased the CM and reduced the TEWL
- HaCaT cell toxicity of Gmoist Sea-Gel
- Gmoist Sea-Gel regulated the CE formation related gene expression
- Gmoist Sea-Gel promoted the FLG degradation
- Gmoist Sea-Gel slightly upregulated AQP-3 gene expressionEn ligne : https://drive.google.com/file/d/1jKk5IrgdBk7as-IStqhBFFLX9mav1AMs/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30956
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Code-barres Cote Support Localisation Section Disponibilité 20161 - Périodique Bibliothèque principale Documentaires Disponible Biotechnologically produced moss active improves skin resilience / Franziska Wandrey in SOFW JOURNAL, Vol. 144, N° 9 (09/2018)
[article]
Titre : Biotechnologically produced moss active improves skin resilience Type de document : texte imprimé Auteurs : Franziska Wandrey, Auteur ; Bernhard Henes, Auteur ; Fred Zülli ; Ralf Reski Année de publication : 2018 Article en page(s) : p. 34-38 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge
Biomolécules actives
Cosmétiques
Hydratation
Peau -- Soins et hygiène
Produits hydratantsIndex. décimale : 668.5 Parfums et cosmétiques Résumé : Mosses substantially helped changing primitive earth into a green planet before vascular plants even existed. They encode genes and proteins for extraordinary resilience long abandoned by higher plants. Biotechnology offers a sterile production of the moss Physcomitrella patens in a reproducible and sustainable way. MossCellTecTm No. 1 is the first biotechnological moss-based product for cosmetic application.
In our research, we have investigated the importance of cell nucleus health as a novel target for anti-aging cosmetics. Interestingly, the moss extract was able to improve the expression of cell nucleus health markers in aged skin cells. Additionally, the active ingredient could improve the hot-humid/cold-dry adaptation of reconstructed skin and improved skin homôgeneity, barrier and hydration despite stressful weather conditions in a placebo-controlled clinicat study. The moss acItive may therefore enhance the general resilience of the skin against environmental changes.Note de contenu : - INTRODUCTION : Moss produced by biotechnology - Cell nucleus health, a novel anti-aging concept
- MATERIALS AND METHODS : Gene expression in old vs. young keratinocytes - Temperature and humidity adaptation of 3D skin model - Skin adaptation in a clinical study
- RESULTS AND DISCUSSION : P. patens extract improves cell nucleus health in aged skin cells - Improved skin adaptation to environmental changesEn ligne : https://drive.google.com/file/d/1keHgHUnCCzRiVne4B_bexmF761ej5Ao5/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30957
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Code-barres Cote Support Localisation Section Disponibilité 20161 - Périodique Bibliothèque principale Documentaires Disponible Compatibility testing of cosmetics and toiletries for babies and children / Alexandra Erlach in SOFW JOURNAL, Vol. 144, N° 9 (09/2018)
[article]
Titre : Compatibility testing of cosmetics and toiletries for babies and children Type de document : texte imprimé Auteurs : Alexandra Erlach, Auteur ; Gunja Springmann, Auteur ; Melanie Renner, Auteur ; Klaus-Peter Wilhelm Année de publication : 2018 Article en page(s) : p. 40-47 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cosmétiques pour enfants
Cosmétiques pour nourrissons
Essais (technologie)
Evaluation
Produits de toilette
Sécurité des produits de consommation
Tests de compatibilitéIndex. décimale : 668.5 Parfums et cosmétiques Résumé : All cosmetic products must be safe, especially those intended for babies and small children. Besides national guidelines and regulations, cosmetic products in the European Union are regulated by the EU Cosmetic Products Regulation. It pays particular attention to protecting the health of vulnerable population groups and recommends a specific assessment for cosmetic products intended for use on children under the age of three years. Nevertheless, standard procedures for the evaluation of the local tolerance are not given. Due to practical and ethical reasons clinical studies on adults should be a first step of compatibility testing. To consider physiological differences notably a not yet fully developed barrier function during the first years of life, barrier function of adult skin can be intentionally compromised by gentle experimental standardized procedures prior product application. As an alternative and depending on the objective target, only pre-screened sensitive subjects are included in the investigation. After extensive pre-examination and testing in adults, tolerance and performance of the final product can also be confirmed with non-incriminating observational studies under normal in-use conditions in children under physician control. Note de contenu : - PHYSIOLOGICAL DIFFERENCES AND CONSEQUENCES
- REGULATORY REQUIREMENTS
- SAFETY EVALUATION OF COSMETICS FOR CHILDRES : Systemic tolerability - Microbiological specifications - Local tolerability
- TEST STRATEGIES - POSSIBILITIES AND LIMITATIONS : Clinical studies on adults - In-use studies on babies and children
- TABLES : 1. SSA/BW ratio for children fro 0 to 10 years (Renwick 1998) - 2. Test designs for different investigations and product classesEn ligne : https://drive.google.com/file/d/1nwAL3xyDyTPxUPNFT4olzc0cyNDDu9-E/view?usp=drive [...] Format de la ressource électronique : Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30958
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