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Mitophagy activation - a novel anti-ageing cosmetic target / Emilio Rubio in SOFW JOURNAL, Vol. 143, N° 6 (06/2017)  

[article]  inSOFW JOURNAL > Vol. 143, N° 6 (06/2017) . - p. 2-9 Titre : Mitophagy activation - a novel anti-ageing cosmetic target Type de document : texte imprimé Auteurs : Emilio Rubio, Auteur ; Miguel Perez-Aso, Auteur ; Jordi Bosch, Auteur ; Ricard Armengol, Auteur ; Blanca Martinez-Teipel, Auteur ; Hagen Döring, Auteur ; Esther Seco, Auteur ; Ana Serrano-Puebla, Auteur ; Patricia Boya, Auteur Année de publication : 2017 Article en page(s) : p. 2-9 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge Dermo-cosmétologie Mitophagie Peau -- Soins et hygiène Index. décimale : 668.5 Parfums et cosmétiques Résumé : Mitophagy is a selective quality control process that targets and degrades damaged mitochondria. Mitophagy is impaired with age, contributing to mitochondrial and cellular dysfunction. Therefore, we hypothesized that boosting mitophagy would keep oxidative toxicity in check and recover function in aged skin cells, thus leading to a visible rejuvenation effect in vivo. Compounds were screened for mitophagy in SH-SY5Y cells with a nove] flow cytometry-based approach. We identified a combination of Paeoniflorin and Trehalose (PF/TH) that synergisticaily induced mitochondrial renewal through mitophagy activation. This activity was confirmed in Normal Human Dermal Fibroblasts (NHDF). A set of assays on NHDF and senescent human dermal fibroblasts were designed to explore cellular responses to mitophagy activation by PF/TH. Our results revealed an anti-ageing activity profile, via restoring collagen to levels found in young cells and reversing other characteristic ageing signs : ATP decrease, MMP-1 release and 8-galactosidase positive cells. Fibroblasts also became more resilient towards mitochondrial damage and oxidative stress, as showed by insults with CCCP and pyrogallol. Finally, a clinical study on aged volunteers confirmed rejuvenating effects achieved by FP/TH active. These results support mitophagy activation as a target for cosmetic anti-ageing applications. Note de contenu : - EXPERIMENTAL : In vitro studies - Clinical study - RESULTS : Mitochondrial recycling : mitophagy - Mitochondrial quality : mitochondrial membrane potential - Mitochondrial function AT° - Oxidative stress - Senescence in ageing models - Ageing markers - In vivo rejuvenating effects En ligne : https://drive.google.com/file/d/1_B4ZN6mvGEsUbrczqA5DjXlEoyp-ZKT2/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28726 [article]

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High-quality collagen from a shiitake-based extract / Julia Comas in SOFW JOURNAL, Vol. 143, N° 6 (06/2017)  

[article]  inSOFW JOURNAL > Vol. 143, N° 6 (06/2017) . - p. 10-12 Titre : High-quality collagen from a shiitake-based extract Type de document : texte imprimé Auteurs : Julia Comas, Auteur ; Cristina Davi, Auteur ; Elena Cañadas, Auteur ; Marine Vincendet, Auteur ; Raquel Delgado, Auteur Année de publication : 2017 Article en page(s) : p. 10-12 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antiâge Champignons et constituants Collagène Cosmétiques Extraits de plantes:Extraits (pharmacie) Lentin du chêne Peau -- Soins et hygiène Index. décimale : 668.4 Plastiques, vinyles Résumé : The well-known shiitake mushroom is believed to present potential rejuvenating benefits, which have led to its recognition as an elixir of life. With a considerable traditional knowledge behind it, the mushroom represents an interesting botanical ingredient with suggested effects in counteracting skin ageing, A new shiitake mushroom-based extract has been recently launched with a specific focus on new targets of the collagen lifecycle, key for a proper protein functionality. The ingredient showed to improve the quality of collagen, while reducing its deterioration and providing a complete care of this important protein for a firmer and younger skin. Note de contenu : - Microarray analysis - Type I collagen induction - Increase in PLOD1 - Decrease in carbamylation - Improvement in collagen structure and organization - Enhancement in firmness En ligne : https://drive.google.com/file/d/1u9UoeaJhHwyb2YuhAJmlA5AP1B9h3U4H/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28727 [article]

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Anti-pollution : olive active hidroxytyrosol / Elena Grau in SOFW JOURNAL, Vol. 143, N° 6 (06/2017)  

[article]  inSOFW JOURNAL > Vol. 143, N° 6 (06/2017) . - p. 14-16 Titre : Anti-pollution : olive active hidroxytyrosol Type de document : texte imprimé Auteurs : Elena Grau, Auteur ; Laura Anton, Auteur Année de publication : 2017 Article en page(s) : p. 14-16 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antioxydants Antiradicalaire Cosmétiques Hydroxytyrosol L'hydroxytyrosol, ou 3,4-dihydroxyphényléthanol (DOPET), est un composé phytochimique phénolique aux propriétés antioxydantes. Ce serait l'un des antioxydants les plus efficaces après l'acide gallique. On le trouve naturellement dans les feuilles d'olivier, qu'on utilise à des fins thérapeutiques en vertu de ses propriétés antibiotiques et d'adjuvant immunologique, mais aussi dans l'huile d'olive sous forme d'oleuropéine, son ester avec l'acide élénolique, ainsi que sous forme libre après dégradation. L'oleuropéine, ainsi que l'oléocanthal, donnent son goût amer à l'huile d'olive vierge extra. Les olives, leur pulpe et les feuilles d'olivier contiennent davantage d'hydroxytyrosol que l'huile d'olive elle-même, à partir desquelles on extrait l'hydroxytyrosol. L'hydroxytyrosol pur est un liquide incolore et inodore. Peau -- Effets de la pollution atmosphérique Peau -- Soins et hygiène Protection cutanée Index. décimale : 668.5 Parfums et cosmétiques Résumé : In order to avoid premature ageing, the best thing we can do it is to protect us from sun and other situations caused by pollution. The urban environment where we live affects to us and our skin. Skin, as we also do, can be stressed, intoxicated and will need a space more oxygenated. In favour of unstoppable situations of industrialization and environmental pollution, which have contributed to destroy the ozone layer, cosmetic laboratories have created new products to combat these factors which are quite harmful to our skin. The result : antipollution cosmetics which are rich in plant extracts to avoid damages and help to protect fibroblasts (tells where the collagen, elastin and hyaluronic acid is produced). The destruction of these vital elements create a decrease of the isotropy in skin, skin dryness and, as a consequence, a premature appearance of wrinkles and spots and matt colour of skin. In this article, the effect of hydroxytyrosol as antioxidant and skin protector against pollution is going to be studied. Firstly, it is necessary to understand that the main problems of pollution are translated in an increase of the ions concentration, lipid peroxidation and free radicals formation. Note de contenu : - Hidroxytyrosol as a chelation of ions - Hidroxytyrosol in lipid peroxidation - Hidroxytyrosol as a neutralizer of free radicals En ligne : https://drive.google.com/file/d/1PdXXK0aw3rBnJ0x3BLfj_DfYddFuQUdW/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28728 [article]

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Multifunctional surfactants - Essential ingredients for efficient cleaning products / Sorel Muresan in SOFW JOURNAL, Vol. 143, N° 6 (06/2017)  

[article]  inSOFW JOURNAL > Vol. 143, N° 6 (06/2017) . - p. 18-22 Titre : Multifunctional surfactants - Essential ingredients for efficient cleaning products Type de document : texte imprimé Auteurs : Sorel Muresan, Auteur ; Adrian Zuberbuehler, Auteur Année de publication : 2017 Article en page(s) : p. 18-22 Langues : Anglais (eng) Catégories : Composés hydrotropes Formulation (Génie chimique) Moussants Produits nettoyants Solubilité Surfactants Index. décimale : 668.1 Agents tensioactifs : savons, détergents Résumé : Beyond their solubilizing property, multifunctional hydrotropes or co-surfactants provide additional value to cleaning formulations. The added value of these multifunctional hydrotropes derives from the synergy with primary surfactants due to low application concentrations, foam control, compatibility with high alkalinity/electrolyte content, reduced environmental impact, low environmental and human toxicity. The product portfolio of AkzoNobel Surface Chemistry includes several classes of multifunctional hydrotropes, such as cationic and amphoteric surfactants, alkyl glucosides and alkyl amide ethoxylates. Note de contenu : - Functionality of hydrotropes - Classes of multifunctional hydrotropes - Increase of cloud point - Improvement of cleaning performance - L&L hard surface cleaning formulations - Household hard surface cleaning formulations - Foaming properties of co-surfactants - Solubility of hydrotropes in alkaline solutions En ligne : https://drive.google.com/file/d/11gsjSx4gilDTH1k0v6XS3_KRhoZLjbpN/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28729 [article]

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Rheological and texture analysis methods for quantifying yield value and level of thixotropy / Slobodanka Tamburic in SOFW JOURNAL, Vol. 143, N° 6 (06/2017)  

[article]  inSOFW JOURNAL > Vol. 143, N° 6 (06/2017) . - p. 24-30 Titre : Rheological and texture analysis methods for quantifying yield value and level of thixotropy Type de document : texte imprimé Auteurs : Slobodanka Tamburic, Auteur ; Helen Sisson, Auteur ; Milica C. Stevic, Auteur ; Neil Cunningham, Auteur Année de publication : 2017 Article en page(s) : p. 24-30 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cosmétiques -- Texture Emulsions -- Emploi en cosmétologie Formulation (Génie chimique) Rhéologie Thixotropie Index. décimale : 668.5 Parfums et cosmétiques Résumé : The objective of this study was to compare different methods for the assessment of yield stress and level of thixotropy in semisolid emulsions, using three instruments ; an air-bearing controlled-stress rheometer, a T-bar viscometer and a texture analyser. The following methods were used to assess the yield stress : a low-rotation T-bar test, a shear stress sweep, a shear rate sweep, an oscillatory stress sweep and an immersion/de-immersion test on the texture analyser. The level of thixotropy was assessed by : a hysteresis loop test, a three-step thixotropy test and a repeated immersion/de-immersion test. A good linear régression fit was found between increasing polymer concentration and yield stress measured by the T bar test, oscillatory stress sweep and immersion/de-immersion test, while no such fit existed in the cases of the shear rate sweep and shear stress sweep. There was good correlation between the two rheological methods for detecting the level of thixotropy, the hysteresis loop and the three-step thixotropy test. The most consistent yield value results were obtained using the low-rotation T-bar test and the oscillatory stress sweep test. Under the experimental conditions of this study, bath three-step thixotropy and hysteresis loop test have proven reliable in assessing the level of thixotropy. The repeated immersion/de-immersion test could also be employed to provide information on irnmediate structural recovery. Note de contenu : - Quantifying the yield stress - Quantifying the level of thixotropy - Table 1. The formulation of the semisolid w/o emulsion used in the study - Table 2. Yield stress values obtained using six different methods, five experimental and one based on mathematical model (Hershel-Buckley equation) En ligne : https://drive.google.com/file/d/1G-wIwT08zGStmeFJJEai0BlJEEbEb8aD/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28730 [article]

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Biocides, solvents and dyes : trends in tormulations and sustainability / Tobias Kimmel in SOFW JOURNAL, Vol. 143, N° 6 (06/2017)  

[article]  inSOFW JOURNAL > Vol. 143, N° 6 (06/2017) . - p. 32-37 Titre : Biocides, solvents and dyes : trends in tormulations and sustainability Type de document : texte imprimé Auteurs : Tobias Kimmel, Auteur ; Thomas Leiblein, Auteur ; Thomas Hofmann, Auteur ; Fred Schambil, Auteur Année de publication : 2017 Article en page(s) : p. 32-37 Langues : Anglais (eng) Catégories : Aérosols Antimicrobiens Colorants Détergents Durée de vie (Ingénierie) Essais (technologie) Produits nettoyants solvants Solvants écologiques Substances dangereuses -- Evaluation du risque Index. décimale : 660 Technologie chimique (chimie industrielle) et techniques connexes Résumé : The annual meeting of the SEPAWA specialist group "Professional Cleaning and Care" was held 23-24 March 2017 in the I council hall of the old town hall of Rapperswil, Switzerland, In a presentation entitled "Lets Go ! Trends in Formulations and Sustainability" the chairman of the group, Prof. Dr Tobias Kimmel, led the audience through the meeting programme. The event was organised with the support of the Zurich University of Applied Sciences. A total of eight lectures focused on biocides, aerosols, new "green" solvents and dyes for liquid formulations, as well as test procedures for detergents and cleaning products. With the aim of making employees more aware of dangers, the programme also featured an impressive experimental lecture entitled "Dangerous Substances Live" which showed the 70 meeting participants hazards in day-to-day practice and pointed out risks. Preparations are already under way for next year's lecture event. The theme and venue of the event will be announced in good time on the SEPAWA website. Note de contenu : - Biocides - Test methods for detergents and cleaning products - New solvents and dyes for liquid formulations - Aerosols En ligne : https://drive.google.com/file/d/12GHQqZAq-ko3ZQSPsOvVL0xqzPUTAvSt/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=28731 [article]

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