Clinical efficacy of a gentle anti-dandruff itch-relieving shampoo formulation / Delwyn Zhi Jie Lim in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 45, N° 6 (12/2023)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 45, N° 6 (12/2023) . - p. 769-774 Titre : Clinical efficacy of a gentle anti-dandruff itch-relieving shampoo formulation Type de document : texte imprimé Auteurs : Delwyn Zhi Jie Lim, Auteur ; Fei Chu Lim, Auteur ; Hong Liang Tey, Auteur Année de publication : 2023 Article en page(s) : p. 769-774 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Antipelliculaires Cheveux -- Soins et hygiène Cosmétiques Dermatite séborrhéique Formulation (Génie chimique) Pellicules (dermatologie) shampooings Index. décimale : 668.5 Parfums et cosmétiques Résumé : Dandruff is a common scalp condition affecting almost half of the world's population. Despite its high prevalence, the exact pathophysiology is not well established and is understood to be multifactorial, with factors such as fungal colonization, sebaceous gland activity and individual factors being implicated. There is a need for an effective and safe shampoo that can target the above factors. Hence, we have developed a shampoo formulation with properties of oil control, moisturizing, non-irritative, anti-fungal, anti-microbial and itch-relieving. In this interventional, open-label study, we evaluated the efficacy and safety of this shampoo in reducing the clinical signs of dandruff and pruritus in patients with pre-existing mild-to-moderate dandruff over a course of 21-day treatment duration through self-assessment and objective clinical evaluations. After continued use of the shampoo, there was a significant decrease in the adherent and loose scalp flaking scores. Mean pruritus scores also decreased significantly across the 21-day time points. There were also no adverse events or skin intolerances reported. This study showed that our shampoo formulation has led to a significant reduction in both adherent and loose scalp flaking and pruritus when used in individuals suffering from mild to moderate dandruff. As such, it is an ideal shampoo, which can be used to effectively control dandruff. Note de contenu : - Introduction and background : Pathophysiology - Addressing a clinical need - Objective - Methods - Mesures and analysis - Results - Table 1 : Demographics of patients - Table 2 : Change in ASFS, loose flaking evaluation score (LFES) and pruritus score DOI : https://doi.org/10.1111/ics.12885 En ligne : https://drive.google.com/file/d/1rNoPXIYHOd8_8WFAXfwnHhGD9PS59ehG/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=40263 [article]

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