The potential prebiotic effect of 2-Butyloctanol on the human axillary microbiome / Min Li in INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Vol. 43, N° 6 (12/2021)  

[article]  inINTERNATIONAL JOURNAL OF COSMETIC SCIENCE > Vol. 43, N° 6 (12/2021) . - p. 627-635 Titre : The potential prebiotic effect of 2-Butyloctanol on the human axillary microbiome Type de document : document électronique Auteurs : Min Li, Auteur ; Katie Truong, Auteur ; Shyamala Pillai, Auteur ; Thomas Boyd, Auteur ; Aixing Fan, Auteur Année de publication : 2021 Article en page(s) : p. 627-635 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : 2-butyloctanol Aisselles -- Soins et hygiène Corynébactéries Cosmétiques Déodorants Microbiote Prébiotiques Staphylocoques Index. décimale : 668.5 Parfums et cosmétiques Résumé : - Objective : The human axilla is colonized by a wide array of microorganisms that contribute to the generation of body odour. Traditional antiperspirant/deodorant products are used to reduce perspiration in the axillary region and to treat or prevent the growth of bacteria in this region, thereby reducing or eliminating body odour. However, they may also compromise the axillary microbiome balance. The personal care industry has been seeking new ingredients, such as prebiotics or probiotics, to maintain a healthy balance of the skin microbiome by inhibiting odour-causing bacteria, whilst maintaining and promoting the growth of good bacteria. The aim of this study was to investigate the prebiotic effect of a skin-care ingredient, 2-butyloctanol, on the human axillary microbiome. - Methods : An in vitro growth inhibition/promotion assay was performed to test whether 2-butyloctanol inhibited or promoted skin bacterial growth. The impact of 2-butyloctanol on the axillary microbiome was also investigated in a human clinical study using 16S rRNA gene sequencing. - Results : In-vitro testing showed that 2-butyloctanol significantly inhibited the growth of corynebacteria at concentrations of 0.64%, 2.56% and 5.12%, whilst the growth of Staphylococcus epidermidis was maintained at the same concentrations. The impact of 2-butyloctanol on the axillary microbiome was also validated in a human clinical study. A deodorant roll-on product containing 3% of 2-butyloctanol significantly reduced the relative abundance of corynebacteria, whilst increasing the relative abundance of Staphylococcus and the ratio of Staphylococcus to corynebacteria after four weeks of application, whilst the placebo showed no significant change. Conclusion : For the first time, it was demonstrated that 2-butyloctanol had a potential prebiotic effect on the human underarm microbiome in inhibiting odour-causing Corynebacterium, whilst maintaining and promoting skin-friendly Staphylococcus in both in-vitro and in-vivo studies. Therefore, 2-butyloctanol could be used as a potential prebiotic ingredient in personal care products for underarm microbiome protection. Note de contenu : - MATERIALS AND METHODS : Growth inhibition/promotion assay - Clinical study design - Bacterial qPCR - 16S rRNA gene sequencing - 16S rRNA gene sequencing data analysis - Statistical analysis - RESULTS : Growth inhibition/promotion assay - Bacterial qPCR - 16S rRNA gene sequencing DOI : https://doi.org/10.1111/ics.12738 En ligne : https://drive.google.com/file/d/1B3bWhmhY8M52miG0w0DfH_eg9fXsPUHA/view?usp=shari [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=37045 [article]

Exemplaires

Code-barres	Cote	Support	Localisation	Section	Disponibilité
aucun exemplaire

---

1 (1 - 1 / 1)