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Identification of skin sensitivity through corneocytes measurements / Naoko Ota in IFSCC MAGAZINE, Vol. 4, N° 1 (01-02-03/2001)
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Titre : Identification of skin sensitivity through corneocytes measurements Type de document : texte imprimé Auteurs : Naoko Ota, Auteur ; Tomoko Horiguchi, Auteur ; Norio Fujiwara, Auteur ; Nobuo Kashibuchi, Auteur ; Yoshikazu Hirai, Auteur ; Fukuyoshi Mori, Auteur Année de publication : 2001 Article en page(s) : p. 9-14 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cornéocytes
Sensibilité cutanée -- Mesure
Tests cutanésIndex. décimale : 668.5 Parfums et cosmétiques Résumé : Surveys conducted in many nations suggest that up to 50% of cosmetic users believe they have sensitive skin and products specifically designed for this skin type have become an important cosmetic category. In developing such products, objective assessment of the degree and the type of sensitivity is desirable. Unfortunately, currently available methods, including measurements of trans-epidermal water loss (TEWL) and lactic acid stinging test do not correlate well with self-assessed sensitivity and cannot be used to identify persons who are more prone to develop adverse skin reactions than other users. A simple, more reliable non- invasive method for detecting skin sensivity is needed.
In developing such a method, it is necessary to understand the exact meaning of "sensitivity" as used by consumers to describe their skin condition. Our extensive survey of 130 subjects, conducted over a one year period and taking into consideration seasonal variations, revealed that the meanig varies somewhat among individuals, but that there is a consensus on specific skin conditions to which they refer when they reort having sensitive skin. These conditions include tendencies for their skin to itch, develop redness and become dry and flaky. Our investigations revealed that the development ok skin sensitivity is often related to reduction in the barrier function of stratum corneum and thus a method could be developed by using certain biophysical properties af corneocytes to predict skin sensitivity. Our search for such an objectively measurable sensitivity index led us to average projected area of corneocytes obtained via tape stripping at a specific area of facial skin can be used for this purpose. Our new method, called APAc method, is more reliable and convenient in predicting self-assessed skin sensitivity than are TEWL or lactic acid stinging test.Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10759
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