The reproducibility of an in-vitro determination of the UVA INDEX describing the relative UVA protection of sun care products / DGK in IFSCC MAGAZINE, Vol. 5, N° 3 (07-08-09/2002)

[article]  inIFSCC MAGAZINE > Vol. 5, N° 3 (07-08-09/2002) . - p. 161-166 Titre : The reproducibility of an in-vitro determination of the UVA INDEX describing the relative UVA protection of sun care products Type de document : texte imprimé Auteurs : DGK, Auteur ; Task Force "Sun Protection", Auteur Année de publication : 2002 Article en page(s) : p. 161-166 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Produits antisolaires Tags : 'UVA  INDEX'  protection'  'Méthode  de  test  In-vitro'  'Protection  solaire'  Reproductibilité Index. décimale : 668.5 Parfums et cosmétiques Résumé : Due to overexposure to UVA and not only to UVB light significant alterations in damage to human skin were observed. Accordingly, the protection against UVA is a major additional requirement for sunscreens beside the effective prevention of sunburn. Despite the intensive debate on the appropriate measurement and labeling, up to now, no proposal was officially accepted in Europe and US. The recently published determination of the in-vitro PPD protection factor [1] was discerned as a candidate for future, harmonized UVA protection measurement? The method combines the merits of in-vitro as well as of in-vivo determinations. The aim of the present study was to investigate the inter-institutional reproducibility of the new UVA parameter and to determine how to express the UVA protection. Concerning the latter aspect, particular emphasize should be given to the importance of the SPF by describing the UVA protection in relation to the UVB protection efficacy. Seven laboratories participated in the Round Robin study and five marketed sunscreen formulations were tested. The sunscreens were selected to represent the major types of sun protection products. The application amount was fixed at 0.75mg/cm2 for all samples and for all institutes after ensuring in a pretest that the absorbance does not exceed the value of 2.0, because otherwise saturation phenomena could occur. Regarding the calculation of the in-vitro PPD protection factors, a high reproducibility was found. The average standard deviation for all five products was less than 15%. The good correlation between in-vitro and in-vivo PPD factors confirms the relevance of this methods. The UVA INDEX was defined as the relation between the in-vitro PPD factor and the labeled in-vivo SPF. Based on the simple transmission measurement and a calculation that takes into account the in-vivo effectiveness as references, it provides a rapid and valid procedure to evaluate and to differentiate the UVA protection of sunscreens. According to these findings, the UVA INDEX is seen as a potential candidate for UVA determinations. Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10639 [article]

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