| Titre : |
In vivo and in vitro SPF determination - Two sides of the same coin ? |
| Type de document : |
texte imprimé |
| Année de publication : |
2012 |
| Article en page(s) : |
p. 97-103 |
| Note générale : |
Bibliogr. |
| Langues : |
Anglais (eng) |
| Catégories : |
Cosmétiques
Produits antisolaires
|
| Tags : |
'Facteur protection solaire' SPF 'In vivo' vitro' 'Application antisolaire' 'Protection UV' |
| Index. décimale : |
668.5 Parfums et cosmétiques |
| Résumé : |
For the purpose of evaluating the risk for consumers who apply less sunscreen than the standard test application amount, the DGK Task Force. "Sun protection" initiated a multicenter study in accordance with the in vivo test protocol of the International Sun Protection Factor (SPF) Test Method. Three different amounts (0.5, 1.0 and 2.0 mg/cm2) of three commercial sunscreens were investigated in three test centers. The main result obtained was a linear dependence of the SPF on the quantity applied. The recommendation to use an application quantity of 2.0 mg/cm2 is clearly driven by the aim to produce reliable and reproducible in vivo resluts. In the subsequent in vitro multicenter study, possible methodologies and strategies for improved accuracy of the determination of the SPF on sandblasted PMMA plates were compared. Influencing factors such as the amount of product applied, pretreatment of the samples, equilibration time and temperature, and the quality of the spectrophotometer were taken into account. An overall decrease in the standard deviations within single laboratories could be achieved for in vitro SPF testing but no improvement in the span of interlaboratory differences was obtained.
The complete findings obtained from this multicenter study could perhaps serve as a solid basis for increasing the reliability of a future in vitro SPF method. |
| Note de contenu : |
- In vivo multicenter study
- Basic application procedures
- Correlation of applied amount of sunscreen and SPF in vitro
- Attempts to harmonize the application procedure
|
| Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=14970 |
in IFSCC MAGAZINE > Vol. 15, N° 2 (04-05-06/2012) . - p. 97-103
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In vivo and in vitro SPF determination - Two sides of the same coin ? in IFSCC MAGAZINE, Vol. 15, N° 2 (04-05-06/2012)
