Fabrication and characterization of electrospun thermoplastic polyurethane/fibroin small-diameter vascular grafts for vascular tissue engineering / E. Yu in INTERNATIONAL POLYMER PROCESSING, Vol. XXXI, N° 5 (11/2016)  

[article]  inINTERNATIONAL POLYMER PROCESSING > Vol. XXXI, N° 5 (11/2016) . - p. 638-646 Titre : Fabrication and characterization of electrospun thermoplastic polyurethane/fibroin small-diameter vascular grafts for vascular tissue engineering Type de document : texte imprimé Auteurs : E. Yu, Auteur ; J. Zhang, Auteur ; J. A. Thomson, Auteur ; Lih-Sheng Turng, Auteur Année de publication : 2016 Article en page(s) : p. 638-646 Note générale : Bibliogr. Langues : Anglais (eng) Catégories : Cellules -- Cultures et milieux de culture Electrofilature Fourier, Spectroscopie infrarouge à transformée de Ingénierie tissulaire Polymères en chirurgie Polymères en médecine Polyuréthanes Protéines végétales Prothèses Prothèses vasculaires Soie et constituants Technologie médicale Textiles et tissus à usages médicaux Textiles et tissus à usages techniques Textiles et tissus à usages techniques -- Propriétés mécaniques Index. décimale : 668.4 Plastiques, vinyles Résumé : The demand for small-diameter blood vessel substitutes has been increasing due to a shortage of autograft vessels and problems with thrombosis and intimal hyperplasia with synthetic grafts. In this study, hybrid small-diameter vascular grafts made of thermoplastic polyurethane (TPU) and silk fibroin, which possessed a hybrid fibrous structure of an aligned inner layer and a random outer layer, were fabricated by the electrospinning technique using a customized striated collector that generated both aligned and random fibers simultaneously. A methanol post-treatment process induced the transition of fibroin protein conformation from the water-soluble, amorphous, and less ordered structures to the water-insoluble ?-sheet structures that possessed robust mechanical properties and relatively slow proteolytic degradation. The methanol post-treatment also created crimped fibers that mimicked the wavy structure of collagen fibers in natural blood vessels. Ultrafine nanofibers and nanowebs were found on the electrospun TPU/fibroin samples, which effectively increased the surface area for cell adhesion and migration. Cyclic circumferential tensile test results showed compatible mechanical properties for grafts made of a soft TPU/fibroin blend compared to human coronary arteries. In addition, cell culture tests with endothelial cells after 6 and 60 days of culture exhibited high cell viability and good biocompatibility of TPU/fibroin grafts, suggesting the potential of applying electrospun TPU/fibroin grafts in vascular tissue engineering. Note de contenu : - CELL CULTURE AND SEEDING - RESULTS AND DISCUSSION : Fourier transform infrared spectroscopy - Structure and morphology - Mechanical properties - Cell culture results DOI : 10.3139/217.3247 En ligne : https://drive.google.com/file/d/194seUjb8XJD2n49MLWsSuLnGz-z9Vk8L/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=27401 [article]

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Main arteries from the printer / Yannick Schwab in KUNSTSTOFFE INTERNATIONAL, Vol. 108, N° 4 (04/2018)  

[article]  inKUNSTSTOFFE INTERNATIONAL > Vol. 108, N° 4 (04/2018) . - p. 32-34 Titre : Main arteries from the printer : The Medical Center of the University of Mainz improves vascular surgery with 3D printed patient specific models Type de document : texte imprimé Auteurs : Yannick Schwab, Auteur Année de publication : 2018 Article en page(s) : p. 32-34 Langues : Anglais (eng) Catégories : Impression tridimensionnelle Polymères en médecine Prothèses vasculaires Index. décimale : 668.4 Plastiques, vinyles Résumé : When surgeons operate on the aorta, they generally rely on computer tomographic images. For the first time, a team at the Medical Center of the Johannes Gutenberg University of Mainz, Germany, has applied the 3D printing process to visualize and diagnose complex conditions more quickly. Transparent 3D models support a better understanding of diseases and also serve to train future vascular surgeons. Note de contenu : - Visualizing complex cases better - 40 percent time-saving in the operation - Success thanks to further training - Fig. 1. Transparent 3D printed model of a patient-specific aortic arch used at the Medical Center of the University of Mainz for working out complex endovascular operations - Fig. 2. Surgeons use a 3D printed model to practice maneuvering and implanting a stent in the complex arteries of a patient En ligne : https://drive.google.com/file/d/1HaUNeGFXlfDD8eDVw5sshneI5nqWtAg0/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=30488 [article]

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