[article]
Titre : |
Double approach to improve epidermal barrier function |
Type de document : |
texte imprimé |
Auteurs : |
David Boudier, Auteur ; S. Mazalrey, Auteur ; Sandrine gofflo, Auteur ; E. Vignau, Auteur ; Brigitte Closs, Auteur |
Année de publication : |
2010 |
Article en page(s) : |
p. 29-33 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Epiderme Extraits de plantes:Extraits (pharmacie) Levures (botanique) Peau -- Soins et hygiène Plantes -- Emploi en cosmétologie Protection cutanée
|
Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
The process of synthesis, transport, secretion and maturation of epidermal lipids is a dynamic equilibrium ensuring homeostasis of the barrier function. The production of lamellar bodies, which release their lipid contents into the intercellular spaces, continuously regenerates the lipid cement of the stratum corneum and also responds to alterations that might damage it. Then, it has been recently accepted that, in addition to the stratum corneum, intercellular junctions -and, especially, Tight Junctions (TJs) - also play a role in homeostasis of the skin barrier function (1,2) by ensuring cohesion between the keratinocytes of the Stratum Granulosum, and secondly, by regulating epidermal Ca2+ gradient and polarized lipids bodies transport (3). This article tackles a double approach for improving the epidermal barrier function by increasing the dynamic flow of lipids and by stimulating cohesion of the epidermis. The author proposes an associationof two natural active ingredients stimulating these biological ways in order to form an absolute barrier function. |
Note de contenu : |
- TARGET 1 : flow of lipids
- EFFECT OF THE PICHIA ANOMALA EXTRACT ON THE FLOW OF LIPIDS : Stimulation of expression of FATP-3, glucosylceramide synthase and ABCA-12 - Enhancement of the ?-glucocerebrosidase activity
- TARGET 2
- EFFECT OF THE OPHIOPOGON JAPONICUS ROOT EXTRACT ON EPIDERMAL TIGHT JUNCTIONS : Synthesis of ZO-1 and claudin-1 - Synthesis of 20-1 by fluorescence microscopy
- ABSOLUTE SKIN BARRIER FUNCTION : Effect of the combination of the Pichia anomala extract with the Ophiopogon japonicus root extract on Trans Epidermal Water Loss (TEWL) |
En ligne : |
https://drive.google.com/file/d/17SFZKZrBqd2mOuxbV5NytT78PzHbkv-K/view?usp=drive [...] |
Format de la ressource électronique : |
Pdf |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=13486 |
in PERSONAL CARE EUROPE > Vol. 3, N° 1 (03/2010) . - p. 29-33
[article]
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